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Intraoperative Off-Label Reversal of Apixaban by Andexanet Alfa while on VA-ECMO Immediately After Emergent Surgery for Acute Type A Aortic Dissection
There is currently no information available on either safety issues or efficacy related to the off-label use of andexanet alfa when given after prior administration of prothrombin complex concentrate, which has been discouraged so far, and in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO).