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Normoxic Re-Oxygenation Ameliorates End-Organ Injury After Cardiopulmonary Bypass
Normoxic reperfusion ameliorates cardiac, renal and neural injury compared with hyperoxic reperfusion in an in vivo animal model of CPB and cardioplegic arrest. This protective effect of normoxic reperfusion may be due to a reduction in signaling pathways for OS, inflammation, and apoptosis.
Diagnosis and Management of Circulatory Arrest in Pediatric Ventricular Assist Device Patients: Presentation of Two Cases and Suggested Guidelines
Pediatric patients supported by ventricular assist devices (VADs) are becoming more common. No guidelines exist to provide an approach to diagnosis or management of circulatory arrest in these patients. We present two case reports of apparent circulatory arrest in pediatric VAD-supported patients at our institution.
Femoral Veno-Arterial Extracorporeal Life Support with Minimal or No Heparin
Recent technological advances in cardiopulmonary bypass circuits achieving surface bonding with heparin have permitted prolonged extracorporeal life support (ECLS) in experimental studies without the use of systemic anticoagulation.
