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Hemoadsorption Eliminates Remdesivir from the Circulation: Implications for the Treatment of COVID-19
Both antiviral treatment with remdesivir and hemoadsorption using a CytoSorb® adsorption device are applied in the treatment of severe COVID-19. The CytoSorb® adsorber consists of porous polymer beads that adsorb a broad range of molecules, including cytokines but also several therapeutic drugs. In this study, we evaluated whether remdesivir and its main active metabolite GS-441524 would be adsorbed by CytoSorb®.
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Is There a “Safe” Suction Pressure in the Venous Line of Extracorporeal Circulation System?
The gaseous cavitation in centrifugal pumps is a phenomenon that appears with decreasing inlet pump pressures.
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Cytoreductive Surgery and HIPEC for Peritoneal Metastases Combined with Curative Treatment of Colorectal Liver Metastases: Systematic Review of all Literature and Meta-Analysis of Observational Studies
A systematic literature search according to the PRISMA guidelines was conducted using the PubMed database of the U.S. National library of Medicine using the keywords: colorectal cancer, liver metastasis, extra-hepatic, peritoneal metastases, peritoneal carcinomatosis, cytoreductive surgery (CRS), HIPEC and combinations hereof.
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