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Safety and Efficacy of Prothrombin Complex Concentrate as First-Line Treatment in Bleeding after Cardiac Surgery
Bleeding after cardiac surgery requiring surgical reexploration and blood component transfusion is associated with increased morbidity and mortality. Although prothrombin complex concentrate (PCC) has been used satisfactorily in bleeding disorders, studies on its efficacy and safety after cardiopulmonary bypass are limited.
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Protamine Test Dose: Impact on Activated Clotting Time and Circuit Integrity
Regardless of the protamine test dosage, there is no reliable way to predict how a patient’s ACT will respond to a protamine test dose. Clot formation and circuit integrity is at risk when pump suction devices are continuously in use during PTD administration. Therefore, we strongly recommend that the direct recovery of mediastinal shed blood into the pump circuit be discontinued before any amount of protamine is administered to the patient.
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Effect of Platelet-Rich Plasma on the Early Bone Formation Around Ca-P-Coated and Non-Coated Oral Implants in Cortical Bone
The purpose of the present study was to investigate the effect of local application of platelet-rich plasma (PRP) on the early healing of cortical bone around Ti implants with two different surface configurations.
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