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Blood Substitutes: Evolution from Non Carrying to Oxygen-and Gas-Carrying Fluids
The development of oxygen (O2)-carrying blood substitutes has evolved from the goal of replicating blood O2 transport properties to that of preserving microvascular and organ function, reducing the inherent or potential toxicity of the material used to carry O2, and treating pathologies initiated by anemia and hypoxia.
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First Successful Open-Heart Surgery Utilizing Cross-Circulation in 1954
We describe this patient’s medical history, and present unique images of internal/external cardiac anatomies and implanted devices obtained via direct visualizations, computed tomography, and fluoroscopy post-mortem.
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