Mesenchymal Stem Cell Therapy in Osteoarthritis: Advanced Tissue Repair or Intervention with Smouldering Synovial Activation
Desando and co-workers report in Arthritis Research & Therapy that intra-articular delivery of adipose-derived stem cells attenuates progression of synovial activation and joint destruction in osteoarthritis in an experimental rabbit model. Clinical studies are warranted to see whether this approach might be a novel way to combat development of joint destruction in inflammatory subtypes of osteoarthritis.