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Influence of Administration of Mesenchymal Stromal Cell on Pediatric Oxygenator Performance and Inflammatory Response
The administration of mesenchymal stromal cells does not interfere with oxygenator function. Allogeneic mesenchymal stromal cells show no immunogenicity, and increase plasma IL-6 level during ex vivo circulation. Further investigation is necessary to determine the effect of mesenchymal stromal cell delivery through CPB during pediatric cardiac surgery.
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Risks of Harms Using Antifibrinolytics in Cardiac Surgery: Systematic Review and Network Meta-Analysis of Randomised and Observational Studies
Although meta-analyses of randomised controlled trials were largely inconclusive, inclusion of observational data suggest concerns remain about the safety of aprotinin.
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