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Hemostatic Resuscitation for Massive Bleeding: The Paradigm of Plasma and Platelets – A Review of the Current Literature
Continued hemorrhage remains a major contributor of mortality in massively transfused patients and controversy regarding the optimal management exists. Recent studies indicate a possible survival benefit in patients receiving a higher ratio of plasma and platelets (PLTs) to red blood cells (RBCs) than what is recommended in current transfusion guidelines.
Can Extra Protamine Eliminate Heparin Rebound Following Cardiopulmonary Bypass Surgery
Postoperative protamine infusion was able to almost totally abolish heparin rebound. In the context of this study, protamine infusion resulted in reduced postoperative bleeding but the magnitude was insufficient to alter transfusion requirements.
