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Perfusion Guidelines: Neurological, Temperature, Renal, Inflammation (EP Video)
Dr. Robert Baker and David Fitzgerald discusses current evidence-based perfusion guidelines on a few different subjects (78:10 minutes).
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Persistent Cognitive Deficits and Neuroinflammation In A Rat Model of Cardiopulmonary Bypass
By using an established rat model of CPB that does not display neuronal loss, we examined behavioral and structural effects of CPB at 6 months postsurgery. Persistent deficits in performance on a complex behavioral task and sustained activation of macrophages/microglia were observed with no evidence of neuronal loss.
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The Effect of Low Tidal Volume Ventilation on Inflammatory Cytokines During Cardiopulmonary Bypass
Our findings suggest that low tidal volume ventilation may reduce the inflammatory response during CPB. Although the benefit of low tidal volume ventilation in CPB has been shown to decrease postoperative lung complications such as pleural effusion, atelectasis and pneumonia, we still lack more definitive and clear proofs of inflammatory cytokines encountered during CPB.
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