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Shear Stress Associated with Cardiopulmonary Bypass Induces Expression of Inflammatory Cytokines and Necroptosis In Monocytes
Our study identifies a shear-stress modulated molecular mechanism that drives systemic inflammation in pediatric CPB patients. These are also the first data to demonstrate that shear-stress causes necroptosis. Finally, we observe that calcium and TNFα signaling are novel targets to ameliorate post-CPB inflammation.
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U.S. FDA Approves Miniature LVAD for Children
The U.S. Food and Drug Administration said on Thursday it had granted a special exemption for a miniature heart device to keep […]
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Blood conservation Strategies in Cardiac Valve Replacement: A Retrospective Analysis of 1645 Patients
We aimed to evaluate whether blood conservation strategies including intraoperative autologous donation (IAD) could reduce perioperative blood transfusion for patients undergoing cardiac valve replacement including mitral valve replacement, aortic valve replacement (AVR), and double valve replacement (DVR).
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