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The Association of Matrix Metalloproteinases With Acute Kidney Injury Following CPB-Supported Cardiac Surgery
Although the pilot study may have limitations, it has demonstrated that the serum and urine levels of activity of MMP-2 and MMP-9 are associated with the clinical endpoint of AKI and appear to have earlier rising levels as compared with those of serum creatinine. Furthermore, in depth, exploration is underway with a larger sample size to attempt validation of the analytical performance and reproducibility of the assay for MMP-2 and MMP-9 to aid in earlier diagnosis of AKI following CPB-supported cardiac surgery.
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Estimation Model for Hypothermic Circulatory Arrest Time to Predict Risk in Total Arch Replacement
As with the actual hypothermic circulatory arrest time, the predicted hypothermic circulatory arrest time using our model detected significant factors associated with major adverse outcomes. These results indicated that this prediction model for hypothermic circulatory arrest time may be effective.
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Harvest Technologies’ case in the U.S. District Court in Massachusetts is proceeding to trial November 29th on the issue of the invalidity of Cytomedix, Inc’s U.S. Patent No. 5,165,938
Harvest Technologies’ case in the U.S. District Court in Massachusetts is proceeding to trial on the issue of the invalidity of Cytomedix, Inc’s U.S. Patent No. 5,165,938 (the Knighton Patent).
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