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This randomized clinical trial found that the study protocols were feasible. Adequately powered randomized clinical trials are warranted to determine whether PCC is a suitable substitute for FP for mitigation of bleeding in cardiac surgery.
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Detection and decontamination of Mycobacterium Chimaera and Other Non-tuberculosis Mycobacteria in Heater–cooler Devices Used in Cardiopulmonary Bypass: a Manufacturer and National Guidelines Summary, and a Potential Resolution to the Problem Requiring Further Investigation
Since 2011, invasive infections due to Mycobacterium chimaera have been diagnosed in patients with previous cardiac surgery.
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Nafamostat Mesilate, As a Treatment for Heparin Resistance, Is not Associated with Perioperative Ischemic Stroke in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass
No evidence was found that nafamostat mesilate was associated with perioperative ischemic stroke in heparin-resistant patients undergoing cardiac surgery with cardiopulmonary bypass.
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