Hereditary AT Deficiency & the Use of Thrombate III (EP Video)

Balanced Regulation of mRNA Production for Fas and Fas Ligand in Lymphocytes From Centenarians. How the Immune System Starts Its Second Century

Lymphocytes from centenarians are able to balance the production of proapoptotic (mFas and FasL) and antiapoptotic (sFas) molecules, whose proportions are likely crucial for the well-preserved immune functionality at the extreme limits of human life.

Bivalirudin for Alternative Anticoagulation in Extracorporeal Membrane Oxygenation

Extracorporeal membrane oxygenation (ECMO) offers therapeutic options in refractory respiratory and/or cardiac failure. Systemic anticoagulation with heparin is routinely administered. However, in patients with heparin-induced thrombocytopenia or heparin resistance, the direct thrombin inhibitor bivalirudin is a valid option and has been increasingly used for ECMO anticoagulation. We aimed at evaluating its safety and its optimal dosing for ECMO.