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Platelet-rich plasma (PRP) and platelet-poor plasma (PPP) have been used to improve hemostasis and wound healing after surgery; however, randomized controlled trials proving their efficacy are lacking.
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Goal-Directed Perfusion to Reduce Acute Kidney Injury after Paediatric Cardiac Surgery (GDP-Akip): Study Protocol for A Prospective Randomised Controlled Trial
In total, 166 paediatric patients undergoing cardiac surgery will be randomly allocated to the GDP group or control group. Patients in the GDP arm will be treated with a GDP strategy during CPB aimed to maintain DO2i at ≥360 mL/min/m2 .
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