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Healthcare Reform for Dummies (EP Video)

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Acute Kidney Injury in Cardiac Surgery

Current evidence supports a multimodal risk-stratification approach with biomarker-guided management of high-risk patients, perioperative administration of dexmedetomidine, and implementation of a care bundle as recommended by the Kidney Disease: Improving Global Outcomes group.

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Calcium Cycling Proteins and Heart Failure: Mechanisms and Therapeutics

Ca2+-dependent signaling is highly regulated in cardiomyocytes and determines the force of cardiac muscle contraction. Ca2+ cycling refers to the release and reuptake of intracellular Ca2+ that drives muscle contraction and relaxation.

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Ketamine as a Neuroprotective and Anti-Inflammatory Agent in Children Undergoing Surgery on Cardiopulmonary Bypass: a Pilot Randomized, Double-Blind, Placebo-Controlled Trial

We hypothesized that ketamine, via N-methyl D-aspartate receptor blockade and anti-inflammatory effects, would reduce central nervous system injury during cardiopulmonary bypass.