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Coagulation Cascade (V.1)
Intrinsic Pathway The coagulation cascade is initiated when blood becomes traumatized by exposure to a foreign surface. An example of this […]
Save It-Don’t Waste It! Maximizing Utilization of Erythrocytes From Previously Stored Whole Blood
Salvaged pRBCs from previously stored whole blood accumulate the red blood cell storage lesion in a similar fashion to standard pRBCs and maintain consistent coagulability when reconstituted with plasma. Salvaged pRBCs are not associated with an increased inflammatory response when used for resuscitation in a murine model. Salvaged pRBCs may be a viable product for utilization in the treatment of traumatic hemorrhagic shock.
The Influence of Platelet-Derived Products on Angiogenesis and Tissue Repair: A Concise Update
Platelet degranulation allows the release of a large amount of soluble mediators, is an essential step for wound healing initiation, and stimulates clotting, and angiogenesis.