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Decreased Erythrocyte Deformability After Transfusion and the Effects of Erythrocyte Storage Duration
The findings demonstrate that increased duration of erythrocyte storage is associated with decreased cell membrane deformability and that these changes are not readily reversible after transfusion.
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Eight Hours of Cold Static Storage with Adenosine and Lidocaine (Adenocaine) Heart Preservation Solutions: Toward Therapeutic Suspended Animation
Our aim was to investigate the effects of 8 hours of cold static storage (4°C) using 2 normokalemic, polarizing adenosine-lidocaine (Adenocaine; Hibernation Therapeutics Global Ltd, Kilquade, Ireland) solutions and to compare their functional recovery with hearts preserved in gold standard histidine-tryptophan-ketoglutarate (Custodiol-HTK; Essential Pharma, Newtown, Pa) and Celsior (Genzyme, Cambridge, Mass) solutions.
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Hemochromatosis Alters the Sensitivity of Red Blood Cells to Mechanical Stress
Given that blood products are commonly exposed to high‐shear environments (eg, during high‐volume transfusion), venesections from asymptomatic and untreated individuals with HH appear suboptimal for the development of therapeutic RBCs.
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