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Pathophysiology of Takotsubo Syndrome: JACC State-of-the-Art Review
A comprehensive understanding of TTS pathophysiology and evidence-based treatments are lacking, and specific and effective treatments are urgently required. This paper reviews the pathophysiology of this fascinating syndrome; what is known from both clinical and preclinical studies, including review of the evidence for microvascular dysfunction, myocardial beta-adrenergic signaling, inflammation, and electrophysiology; and where focused research needs to fill gaps in understanding TTS.
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Efficacy and Cost-Effectiveness of Cell Saving Blood Autotransfusion in Adult Lumbar Fusion
The objective of this study was to explore the use of cell saver blood autotransfusion in spinal surgery and to evaluate the efficacy and cost-effectiveness of cell saver blood autotransfusion during lumbar spine fusion in adults.
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Harms Associated with Single Unit Perioperative Transfusion: Retrospective Population Based Analysis
The objective of this study was to determine whether perioperative transfusion of as little as one unit of packed red blood cells in the operating room or the day after surgery is associated with measurably increased odds for perioperative ischemic stroke and myocardial infarction.
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