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Pulmonary and Systemic Vascular Resistances After Cardiopulmonary Bypass: Role of Hemolysis
Prolonged cardiopulmonary bypass (CPB) is associated with hemolysis, resulting in increased plasma oxyhemoglobin and vascular nitric oxide depletion.
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Respiratory Dialysis—A Novel Low Bicarbonate Dialysate to Provide Extracorporeal Co2 Removal
Bicarbonate dialysis results in Co2 removal at rates comparable with existing low-flow extracorporeal Co2 removal in a large animal model, but the final dialysis dose delivered needs to be reduced before the technique can be used for prolonged periods.
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I-PASS Handover System: A Decade of Evidence Demands Action
Thus, consistent with all previous studies, I-PASS was implemented successfully and handover quality improved. However, is the lack of association of I-PASS implementation with clinical outcomes and adverse events in this study a concern? To answer this question, it is necessary to review the origins of I-PASS more than a decade ago and its continually expanding evidence base.
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