Platelet Aggregation in Whole Blood is Not Impaired by A Platelet-Sparing Leukoreduction Filter and Instead Depends Upon the Presence of Leukocytes
WB filtration results in platelet count reduction and leukocyte removal; however, platelet IA is not degraded by passage through the filter. Apparent declines in platelet IA responses can be fully attributed to the reduction in platelet count and the removal of leukocytes.