Acute Isotonic Hyponatremia After Single Dose Histidine-Tryptophan-Ketoglutarate Cardioplegia: An Observational Study
Administration of histidine-tryptophan-ketoglutarate cardioplegia during cardiac surgery leads to acute moderate to severe isotonic hyponatremia, which resolves spontaneously in the first 18 hours perioperatively. Correction with hypertonic saline is not necessary.