Fibrinolysis and the Influence of Tranexamic Acid Dosing in Cardiac Surgery
The assessment of the fibrinolytic status may have the potential to facilitate dose-adjusted antifibrinolytic therapy in the future.
Intraoperative Hemoadsorption in Patients With Native Mitral Valve Infective Endocarditis
These data suggest that intraoperative hemoadsorption may improve surgical outcome in patients with mitral valve endocarditis.
Risk Factors for Complete Recovery of Adults After Weaning from Veno-Venous Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Failure: An Analysis from Adult Patients in The Extracorporeal Life Support Organization Registry
Complete recovery after veno-venous ECMO support is associated with the patient’s baseline condition, ECMO duration, and ECMO-related complications. Respiratory ECMO should aim to increase both the survival and the quality of life after weaning from ECMO.
Near-Infrared Spectroscopy in Adult Circulatory Shock: A Systematic Review
Near-infrared spectroscopy-derived StO2 can predict mortality in circulatory shock, but high-quality data on the impact of NIRS monitoring are lacking.
Mobilizing Carbon Dioxide Stores: An Experimental Study
CO2 from body stores can be mobilized over 48 hours without reaching a steady state. This provides a physiological rationale for intermittent ECCO2R in chronically hypercapnic patients.
ECCO2R Therapy in the ICU: Consensus of A European Round Table Meeting
Insights from this group of experienced physicians suggest that ECCO2R therapy may be an effective supportive treatment for adults with ARDS or ae-COPD. Further evidence from randomised clinical trials and/or high-quality prospective studies is needed to better guide decision making.
Sickle Cell-Related Complications in Patients Undergoing Cardiopulmonary Bypass
In this cohort of patients, older age, longer CPB times, lower median temperature, and the utilization of deep hypothermic circulatory arrest appear to play an important role in the development of complications.
Extracorporeal Blood Purification Treatment Options For COVID-19: The Role of Immunoadsorption
Several extracorporeal blood purification therapies are now available, and most of them target endotoxins and/or the cytokines and aim improving the immune response. For this purpose, plasmapheresis and immunoadsorption may be an important adjunctive treatment option to manage the complications caused by cytokine storm in critically ill patients with COVID-19.
Thromboelastography Profiles of Critically Ill Patients With Coronavirus Disease 2019
A large proportion of critically ill patients with coronavirus disease 2019 have hypercoagulable thromboelastography profiles with additional derangements related to fibrinogen and platelet function. As the majority of patients have an elevated thromboelastography maximum amplitude, a follow-up study evaluating platelet aggregation would be instructive.
A Pharmacokinetic and Pharmacodynamic Investigation of an ε-Aminocaproic Acid Regimen Designed for Cardiac Surgery with Cardiopulmonary Bypass
This regimen provided maximum EACA concentrations near the time of protamine administration, with a total perioperative dose of 15 g.
Blood Management in A Patient with Anti-Oka Antibody Who Underwent Cardiac Surgery Using Cardiopulmonary Bypass: A Case Report
Multidisciplinary intraoperative blood management in a patient with anti-Oka antibody facilitated successful cardiac surgery using CPB, along with effective use of limited blood products.
Efficacy of Glyceryl Trinitrate (GTN) To Facilitate the Rewarming Process During Cardiopulmonary Bypass
Higher dose GTN infusion during rewarming on CPB does not improve peripheral-core temperature gradient post operatively and has no effect on post-operative lactate concentrations.