Anticoagulation in Pediatric Extracorporeal Life Support—Time for a More Direct Approach?
Difficulties with UF each include significant in vivo intrapatient and interpatient variability as well as achieving clinical efficacy with a reliable in vitro anticoagulation test.
Comparative Changes of Pre-Operative Autologous Transfusions and Peri-Operative Cell Salvage in The United States
There was a significant decrease in PAD red blood cell transfusions, while PACS has increased and subsequently decreased; PACS plays an important role in surgical blood conservation.
Mobile Extracorporeal Membrane Oxygenation: 5-Year Experience of a French Pediatric and Neonatal Center
We describe one of the largest cohorts of infants and children transported by a mobile unit while on extracorporeal membrane oxygenation. Our findings confirm that it is safe to start extracorporeal membrane oxygenation in a referring center and to transport patients using an extracorporeal membrane oxygenation mobile team.
The Impact of Intraoperative Patient Blood Management on Quality Development in Cardiac Surgery
Real-time laboratory recommendations achieved a high acceptance rate early after initiation. Improvement of clinical outcome by intraoperative PBM adds to the optimized surgical care. However, the corridor between hemostatic optimization and thromboembolic risk may be narrow.
Oxygen and Carbon Dioxide Levels in Patients after Cardiac Arrest
There was no association between exposure to various levels of PaO 2 and PaCO 2 and neurological outcome after cardiac arrest.
Sonographic Muscle Mass Assessment in Patients After Cardiac Surgery
Skeletal quadriceps muscle thickness assessed by ultrasound shows a trend to a decrease in patients after cardiac surgery post-ICU admission and is associated with prolonged duration of MV and ICU length of stay.
Modulating the Bioactivity of Nitric Oxide as a Therapeutic Strategy in Cardiac Surgery
Perspectives for modulation of endothelial function using NO-mediated mechanisms are discussed. Some of these strategies may provide important therapeutic benefits for human cardiovascular interventions.
Desflurane and Sevoflurane Concentrations in Blood Passing Through the Oxygenator During Cardiopulmonary Bypass: A Randomized Prospective Pilot Study
Our results demonstrated that the blood concentrations of desflurane and sevoflurane passing through oxygenators used during CPB were similar to those in the human lung control.
Incidence of Ischemic Optic Neuropathy After Cardiopulmonary Bypass: 20-Year Experience
Practice improvements (eg, transition to membrane oxygenators, blood transfusion guidelines, less- invasive surgical options for high-risk patients) during the time between the authors’ studies likely affected the incidence reduction.
Blood Pressure and Brain Injury in Cardiac Surgery: A Secondary Analysis of A Randomized Trial
A higher mean arterial pressure during CPB was associated with signs of impaired cerebral metabolism, though not at the predefined significance level of 0.01. No significant association was found between metabolite ratio changes and neuroradiological pathology or change in cognitive function.
Use of Factor VIIa and Anti-inhibitor Coagulant Complex in Pediatric Cardiac Surgery Patients
Both rFVIIa and FEIBA reduced blood product usage in pediatric patients following cardiac procedures.
The Use of Hemostatic Blood Products in Children Following Cardiopulmonary Bypass and Associated Outcomes
Larger studies should be performed to determine the hemostatic efficacy of these products, as well as to clarify associated morbidities, in order to inform proper blood management.