Massive Blood Loss Protocol ‘Code Red’ At Papworth Hospital: A Closed Loop Audit
Preparation for and anticipation of massive blood loss has likely decreased the number of incidences requiring ‘Code Red’ activation, permitting delivery of safe patient care.
The Impact of Minimal Invasive Extracorporeal Circulation on Postoperative Kidney Function
Our findings challenge the superiority of minimal invasive compared to conventional extracorporeal circulation in terms of preservation of renal function following low-risk coronary surgery.
Efficacy of Plasma Free Hemoglobin for Detecting Centrifugal Pump Thrombosis
Our results showed the efficacy of pfHb for detecting centrifugal pump thrombosis.
Factors Associated with Errors in The Heparin Dose Response Test: Recommendations to Improve Individualized Heparin Management in Cardiopulmonary Bypass
Based on our analysis, we provide several recommendations and a flow chart to improve the quality of individualized heparin management on CPB.
COVID-19: FAQs in Pediatric Cardiac Surgery—A Sequel
Our knowledge of the COVID-19 pandemic continues to grow rapidly, leading to further clarity and revealing new questions in turn, thus it is critically important that clinician knowledge is updated frequently.
Persistent Cognitive Deficits and Neuroinflammation In A Rat Model of Cardiopulmonary Bypass
By using an established rat model of CPB that does not display neuronal loss, we examined behavioral and structural effects of CPB at 6 months postsurgery. Persistent deficits in performance on a complex behavioral task and sustained activation of macrophages/microglia were observed with no evidence of neuronal loss.
Transfusion in Elective Aortic Root Replacement: Analysis of the STS Adult Cardiac Surgery Database
Elective aortic root replacement can be performed with acceptable requirements for blood products. Composite root replacement has a greater likelihood of transfusion than does a valve-sparing procedure.
Mild AKI Is Associated with Mortality of Patients Who Underwent Cardiopulmonary Bypass Surgery
AKI stage I is the most common form of AKI and it is independently related to all-cause mortality in patients who underwent cardiovascular surgery with cardiopulmonary bypass.
Interaction of Heparin and Protamine in Presence of Overdosage: In Vitro Study
We reconfirmed that the ROTEM device enables discrimination of the effects heparin and protamine on coagulation and detection of the coagulation-impairing effects of protamine overdosage. Furthermore, we were able to show a positive effect on coagulation times by heparin in the presence of protamine overdosage.
ISTH DIC Subcommittee Communication on Anticoagulation In COVID-19
Although the current evidence is still insufficient, we provide a pragmatic approach to anticoagulation in COVID‐19, but stress the need for further trials in this area.
Analysis of Mirrored Psychophysiological Change of Cardiac Surgery Team Members During Open Surgery
In this pilot study, mirrored physiological responses representing peaks in cognitive workload were observed uncommonly across dyads of cardiac surgery team members (1.73 peaks/case on average). Almost half of these occurred during the most technically demanding phases of cardiac surgery, which may underpin teamwork quality.
A Comparative Analysis of Four Activated Clotting Time Measurement Devices in Cardiac Surgery with Cardiopulmonary Bypass
Careful validation must be undertaken when adopting a different method as decision limits would be affected. Clinicians should also be cautious using ACT as the only indicator for full heparin reversal.