A Randomized Controlled Trial of Antithrombin Supplementation During Extracorporeal Membrane Oxygenation
Antithrombin supplementation may not decrease heparin requirement nor diminish the incidence of bleeding and/or thrombosis in adult patients on venovenous extracorporeal membrane oxygenation.
Clinical Controversies in Anticoagulation Monitoring and Antithrombin Supplementation for ECMO
In this clinically focused review, the authors discuss the complexities of anticoagulation monitoring and therapeutic intervention for patients on ECMO and examine the challenges surrounding AT supplementation given both the historical and current perspectives summarized in the literature on these topics.
Artificial Intelligence in Cardiothoracic Surgery
In this review, we discuss the current initiatives that are using AI in cardiothoracic surgery and surgical care in general.
Pericardial fluids or Cardiopulmonary Bypass-Is There a Major Culprit for Changes in Coagulation and Inflammation?
Direct recirculation of pericardial fluids rather than conventional CPB itself causes major intraoperative changes of some coagulation markers. Pericardial blood loss with direct recirculation should be kept to a minimum to avoid unnecessary activation of coagulation.
Venovenous Bypass During Liver Transplantation: A New Look at an Old Technique
Advances in extracorporeal technologies offer new opportunities for VVB in managing critically ill patients in LT. Here, we review these new developments in VVB.
The Need for Clinical Judgement in The Application of Evidence-Based Medicine
In some instances, when there is a lack of evidence, or faulty interpretation of the evidence, clinical judgement should inform the application of EBM.
Establishment of An Extracorporeal Cardio-Pulmonary Resuscitation Program in Berlin – Outcomes Of 254 Patients with Refractory Circulatory Arrest
An eCPR program can be life-saving for a subset of individuals with refractory circulatory arrest, with time to initiation of eCPR being a main determinant of survival.
Clotting Functional Stability of Withdrawing Blood in Storage for Acute Normovolemic Hemodilution: A Pilot Study
Even though the MCE significantly decreased in a time-dependent manner, MCF of FIBTEM and EXTEM was normal up to 24 h storage. The blood of ANH can use for the purpose of hemostasis at least 8 h stored at room temperature after blood withdrawal.
Multi-Modal Cardiopulmonary Bypass Skills Assessment within a High-Fidelity Simulation Environment
Multimodal assessment using cognitive, technical, and motion analysis of basic CPB tasks using a high-fidelity simulation environment is a valid system to measure performance and discriminate experts from trainees.
The Care and Keeping of Clinicians in Quality Improvement
Our findings highlight areas that organizations and professional development programs should focus on to promote clinician development and engagement in quality improvement. Barriers related to training, time, mentorship, organizational support and implementation must be concurrently addressed to augment the effectiveness of other approaches.
Slow Versus Fast Rewarming After Hypothermic Circulatory Arrest: Effects on Neuroinflammation And Cerebral Oedema
The present experimental study demonstrated reduction in the inflammatory response, reduction of inflammatory cell activation in the brain, enhancement of cerebral blood flow and reduction of cerebral oedema when slow rewarming was applied.
Position Paper on Global Extracorporeal Membrane Oxygenation Education and Educational Agenda for the Future: A Statement From the Extracorporeal Life Support Organization ECMOed Taskforce
Significant variability and limitations in global extracorporeal membrane oxygenation education exist. In this position paper, we outline a road map for standardizing international extracorporeal membrane oxygenation education and practitioner certification.