Influence of Blood Haemoglobin Concentration on Renal Haemodynamics and Oxygenation During Experimental Cardiopulmonary Bypass in Sheep
In experimental CPB blood transfusion to increase Hb concentration from ~7 g dL−1 to ~9 g dL−1 did not improve renal cortical or medullary tissue PO2 even though it decreased whole kidney oxygen extraction.
The Effect of Vacuum-Assisted Venous Drainage on Hemolysis During Cardiopulmonary Bypass
There was no significant increase in hemolysis among the groups, which demonstrates that the VAVD technique, even if lower negative pressure is preferred, can be applied safely and effectively to improve venous drainage and consequently, cardiac decompression, even if smaller venous cannulas are used, and also avoid from superfluous fluid addition to sustain adequate extracorporeal perfusion.
Continuous Ultrafiltration During Extracorporeal Circulation and Its Effect on Lactatemia: A Randomized Controlled Trial
The use and control of continuous high-volume hemofiltration through a polyethersulfone membrane during heart-lung surgery could potencially prevent postoperative complications. The reduction of lactatemia implied a reduction in intubation time, a decrease in morbidity and mortality in the intensive care unit and a shorter hospital stay.The use and control of continuous high-volume hemofiltration through a polyethersulfone membrane during heart-lung surgery could potencially prevent postoperative complications. The reduction of lactatemia implied a reduction in intubation time, a decrease in morbidity and mortality in the intensive care unit and a shorter hospital stay.
Shear Stress Associated with Cardiopulmonary Bypass Induces Expression of Inflammatory Cytokines and Necroptosis In Monocytes
Our study identifies a shear-stress modulated molecular mechanism that drives systemic inflammation in pediatric CPB patients. These are also the first data to demonstrate that shear-stress causes necroptosis. Finally, we observe that calcium and TNFα signaling are novel targets to ameliorate post-CPB inflammation.
Newly Developed Pediatric Membrane Oxygenator that Suppresses Excessive Pressure Drop in Cardiopulmonary Bypass and Extracorporeal Membrane Oxygenation (ECMO)
This article developes a pediatric membrane oxygenator that is compact, high performance, and highly safe.
An Evaluation of Hard-Shell Venous Reservoir Integrated Pressure Relief Valve Pressure Mitigation Performance
Significant variability among reservoir’s IPRV to mitigate reservoir pressurization exists.
Sex Differences in Outcomes After Coronary Artery Bypass Grafting
This study demonstrated that female patients who undergo CABG are at a greater risk of in-hospital death and 30-day and 90-day readmission compared with men. This sex-based disparity in outcomes has persisted since identification some 40 years ago.
Myocardial Perfusion and Cardiac Dimensions During Extracorporeal Membrane Oxygenation-Supported Circulation in A Porcine Model of Critical Post-Cardiotomy Failure
Coronary artery blood flow is maintained during venoarterial extracorporeal membrane oxygenation after cardiopulmonary bypass and cardioplegic arrest despite severely affected performance of the left ventricle.
Hematologic Consequences of the Coronavirus Crisis—Focus on Relevant Clues and Complications for the Perioperative Cardiothoracic and Vascular Community
The purpose of this freestanding editorial is to highlight the hematologic consequences of the COVID-19 pandemic as they provide clues and challenges for the delivery of high-quality patient care.
Advanced Age and Sex Influence Baseline Regional Cerebral Oxygen Saturation as Measured by Near-Infrared Spectroscopy: Subanalysis of a Prospective Study
Baseline rScO 2, as measured by the INVOS 5100, decreases with advanced age and is lower in women. New definitions of cerebral oxygen desaturation need to be analyzed in future trials that will evaluate neurologic outcome in the aging population or in women.
Survival Following Venoarterial Extracorporeal Membrane Oxygenation in Postcardiotomy Cardiogenic Shock Adults
Older age, left main coronary artery disease, and vasoactive inotropic score were associated with 36-month mortality in coronary artery bypass grafting patients who received venoarterial extracorporeal membrane oxygenation.