Platelet Administration During Cardiopulmonary Bypass in Neonates: A Universal Therapy Applied in a Novel Way
Improved intraoperative and postoperative hemostasis was observed in neonates given platelets during the rewarming phase of cardiopulmonary bypass.
Routine Presternotomy Extracorporeal Circulation for Redo Surgery
Routine establishment of presternotomy ECC reduces the risk of injury to the mediastinal structures during reentry and facilitates easier repair in the event of structural injury during reentry or dissection.
Extracorporeal Resuscitation with Carbon Monoxide Improves Renal Function by Targeting Inflammatory Pathways in Cardiac Arrest in Pigs
Our data demonstrate improved renal function by extracorporeal CO treatment in a porcine model of cardiac arrest.
Comparison of Three Infant Venous Reservoirs with Vacuum-assisted Venous Drainage During Varying Levels of Cardiotomy Suction
There is an adverse effect of excessive cardiotomy suction on the efficacy of vacuum-assisted venous drainage in infant hard-shell venous reservoirs.
Differential Modulatory Effects of Propofol and Sevoflurane Anesthesia on Blood Monocyte HLA-DR and CD163 Expression During and After Cardiac Surgery with Cardiopulmonary Bypass: a Preliminary Randomized Flow Cytometry Study
Propofol seems to induce a higher postoperative fraction of the CD163highHLA-DRlow monocyte subset.
Antithrombin Supplementation in Adult Patients Receiving Extracorporeal Membrane Oxygenation
Therapeutic anticoagulation occurred more frequently following antithrombin supplementation; however, this difference was not statistically significant. More bleeding events occurred following antithrombin supplementation while observing an increase in platelet transfusions.
Long-term Follow-up of Post-cardiac Surgery Mycobacterium Chimaera Infections: A 5-center Case Series
Given poor response to treatment and potential for delayed relapses, post-cardiac surgery M. chimaera infection warrants aggressive treatment and long-term monitoring.
Altered Frontal White Matter Microstructure is Associated with Working Memory Impairments in Adolescents with Congenital Heart Disease: A Diffusion Tensor Imaging Study
Adolescence, which is a crucial period for prefrontal brain maturation, may offer a window of opportunity for intervention in order to support the maturation of frontal brain regions and therefore improve higher order cognitive function in patients with CHD.
Impact of Custodiol‐N Cardioplegia on Acute Kidney Injury After Cardiopulmonary Bypass
A statistical trend was found showing that AKI‐related proximal tubule swelling and cytochrome c release were diminished.
The Use of Data Science to Analyse Physiology of Oxygen Delivery in the Extracorporeal Circulation
Modern calculation tools make it possible to create a common data platform from a very large database. Using that methodology we created models of haemodynamic compounds describing tissue oxygen delivery.
Carotid artery blood flow velocities during open-heart surgery and its association with delirium
Our results suggest that higher cerebral blood flow velocities after aortic de-clamping and probably also improved brain oxygenation might be beneficial to prevent postoperative delirium.
Pharmacological Interventions to Reduce Edema Following Cardiopulmonary Bypass: A Systematic Review and Meta-analysis
To compare the effectiveness of different types of pharmacological agents to reduce organ specific edema following cardiopulmonary bypass (CPB).