Does the Full-Time Presence of an Intensivist Lead to Better Outcomes in the Cardiac Surgical Intensive Care Unit?
In this large cohort of patients admitted to a dedicated adult cardiac surgery intensive care unit, 24-hour intensivist coverage was associated with reduced mortality among patients with an expected operative mortality 5% or greater.
Heparin Dose and Point-of-Care Measurements of Hemostasis in Cardiac Surgery—Results of a Randomized Controlled Trial
Compared with a lower dose of heparin during CPB, a high dose of heparin had little effect on the point-of-care measurements of hemostasis, TEM, and MEA. Based on the similarity of platelet and coagulation activity assessments, the higher heparin dose does not appear to offer benefit during CPB.
Thrombin Generation and Bleeding in Cardiac Surgery: a Clinical Narrative Review
This narrative review discusses the role of thrombin generation in coagulation and bleeding in cardiac surgery, the laboratory methods for clinical detection of impaired thrombin generation, and the available hemostatic interventions that can be used to improve thrombin generation.
Clotting Time Results Are Not Interchangeable Between EXTEM and FIBTEM on Rotational Thromboelastometry
CyD shortens the onset of TG and clot formation, resulting in shorter CTFIBTEM than CTEXTEM.
Frequency and Outcomes of Elevated Perioperative Lactate Levels in Adult Congenital Heart Disease Patients Undergoing Cardiac Surgery
Currently there is insufficient evidence to use lactate levels as a predictor of outcomes in adult patients with congenital heart disease undergoing cardiac surgery.
The Use of Extracorporeal Membrane Oxygenation in Human Immunodeficiency Virus–Positive Patients: a Review of a Multicenter Database
Survival among patients with human immunodeficiency virus infection who receive extracorporeal membrane oxygenation was less than 40%.
Safety and Efficacy of a Novel Pneumatic-Driven ECMO Device
The pneumatically-driven ECMO device provides excellent safety and physiologic efficacy in a 7-day sheep experiment without visible clotting, hemolysis, or sustained reductions in fibrinogen or platelets.
Mechanical Ventilation Management during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome. An International Multicenter Prospective Cohort
Ultraprotective lung ventilation on ECMO was largely adopted across medium– to high–case volume ECMO centers. In contrast with previous observations, mechanical ventilation settings during ECMO did not impact patients’ prognosis in this context.
The Right Ventricle after Cardiopulmonary Bypass: new Insights on its Adaptive Physiology
Post cardiopulmonary bypass (CPB) right ventricular (RV) dysfunction has been extensively described in cardiac surgery
Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study
Preoperative severe vitamin D deficiency was associated with the occurrence of delirium after coronary artery bypass grafting surgery.
MHCA with SACP versus DHCA in Pediatric Aortic Arch Surgery: A Comparative Study
MHCA + SACP is associated with better short-term outcomes in children receiving aortic arch surgery under CPB.
Contemporary Australian Priming Constituents for Adult Perfusion Centres: a Survey
Contemporary Australian priming practices show a marked level of conformity between units. Variation exists in the rationale for adding sodium bicarbonate, mannitol and albumin.