Importance of Blood Pressure Regulation in Maintaining Adequate Tissue Perfusion
Abstract: Patients undergoing surgery with the aid of cardiopulmonary bypass(CPB)have an incidence of end-organ dysfunction, caused by embolization, regional hypoperfusion, or some […]
Mitral Valve Replacement Still Problematic in Young Children
WESTPORT, CT (Reuters Health) – With the advent of mechanical prostheses, valve failure is no longer a problem after mitral valve replacement […]
Myocardial Protection with Oxygenated Esmolol Cardioplegia During Prolonged Normothermic Ischemia in the Rat
Objective: We previously showed that arrest with multidose infusions of high-dose (1 mmol/L) esmolol (an ultra-short-acting ß-blocker) in oxygenated Krebs-Henseleit buffer (esmolol […]
Should Standard On-Pump Protamine Dosing Formulas Be Recalculated for Off-Pump Coronary Artery Bypass Grafting?
Background: Since 1994 at the authors’ institution, approximately 9000 cardiac surgical procedures were performed using activated clotting time (ACT)-monitored heparin anticoagulation for […]
Meta-Analysis on the Effect of Off-Pump Coronary Bypass Surgery
Objective: To assess the effect of conventional coronary artery bypass surgery (CABG) compared to the off-pump procedure (OPCAB). Methods: Based on randomised […]
Transfusion Protocols for Pediatric Cardiac Patients
OBJECTIVES: Low-hematocrit bypass is one technique used to prevent allogeneic transfusion during cardiopulmonary bypass. The purpose of this study is to determine […]
Platelet-Derived Growth Factors Enhance Proliferation of Human Stromal Stem Cells
Studies on new procedures for bone reconstruction suggest that autologous cells seeded on a resorbable scaffold can improve the treatment of bone […]
Pulmonary Artery Perfusion With Hypothermic Solution Inhibits the Apoptosis of Lung Parenchymal Cells During CPB
OBJECTIVE: To study effects of pulmonary artery perfusion with hypothermic solution on the apoptosis of lung parenchymal cells during cardiopulmonary bypass. METHODS: […]
Rewarm Rate After Cardiac Surgery a Major Factor in Preventing Cognitive Deficits
DURHAM, NC — May 9, 2000 — For years, surgeons have been performing successful open heart surgeries on their patients only to […]
Sirolimus-Eluting Stents Inhibit New and Recurrent Lesions
Sirolimus eluting stents prevent neointimal proliferation in de novo and in in-stent restenosis lesions without inducing positive vascular remodeling, according to a […]
Genes Released From Coated Stents Could Reduce Coronary Artery Restenosis Rates
WESTPORT, CT (Reuters Health) – Localized delivery of genes from coronary artery stents could reduce the risk of restenosis, according to a […]
Evaluation of a Novel Synthetic Sealant for Inhibition of Cardiac Adhesions
Background: Pericardial adhesions subject patients requiring reoperation to potential injuries to the heart, great vessels, and cardiac grafts during the re-sternotomy. These […]