Lessons Learned on A New Procedure: Nonsternotomy Minimally Invasive Pulmonary Embolectomy
The initial data was positive and suggested that this approach is safe and feasible. We now broaden our experience with another two patients who underwent this approach, and highlight a number of technical and management modifications that have been made to optimize the procedure.
Complete Aortic Thrombosis in SARS-Cov-2 Infection
COVID-19 infection due to the SARS-CoV-2 virus has shown to be associated with a hypercoagulable state.
Correlating Oxygen Delivery on Cardiopulmonary Bypass with Society of Thoracic Surgeons Outcomes Following Cardiac Surgery
Low DO2 on bypass may be associated with morbidity/mortality following cardiac surgery, particularly in patients undergoing nonisolated CABG. These results underscore the importance of goal-directed perfusion strategies.
Hypofibrinogenemia Can Be Estimated by The Predictive Formula in Aortic Surgery
The SFL at the termination of CPB in aortic surgery can be predicted by the preoperative SFL, body weight, CPB time and surgical approach. The predictive formula is useful for developing a hemostasis strategy, including preparing for blood transfusion.
Observational Study of Thrombosis and Bleeding In COVID-19 VV ECMO Patients
We observed a high prevalence of VTE and a significant number of hemorrhages in these severely ill patients with COVID-19 requiring veno-venous ECMO support.
The Role of Hyperthermic Intraperitoneal Chemotherapy in Pseudomyxoma Peritonei After Cytoreductive Surgery
In this cohort study, HIPEC was associated with better overall survival when performed after CRS in PMP, generally without adverse effects on surgical outcomes.
Extracorporeal Membrane Oxygenation Versus Mechanical Ventilation Alone in Adults with Severe Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis
This study showed that the ECMO group exhibited a significantly lower mortality rate compared with the MV alone group at 90, 30 and 60 days for severe ARDS patients.
Successful Antithrombin Administration in Andexanet Alfa-Associated Heparin Resistance
During routine CPB, high-dose unfractionated heparin (UFH) prevents consumptive coagulopathy and the formation of thrombi within the CPB circuit and the patient's circulation. Prior treatment with andexanet alfa can pose difficulties in achieving adequate anticoagulation during CPB with UFH. The administration of antithrombin, in combination with UFH, may overcome these difficulties.
Minimum Alveolar Concentration of Sevoflurane as a Single Hypnotic Agent to Maintain BIS Below 50 in Patients During Normothermic Cardiopulmonary Bypass
MACBIS50 of sevoflurane as a single hypnotic agent was 0.82% in patients undergoing CABG during normothermic CPB.
Thromboelastometry, Thromboelastography, and Conventional Tests to Assess Anticoagulation During Extracorporeal Support: A Prospective Observational Study
The aim of the study was to evaluate ROTEM as a tool for assessing hemostasis during ECMO, by comparing it to TEG and conventional coagulation assays.
The Hemovent Oxygenator: A New Low-Resistance, High-Performance Oxygenator
The aim of the current animal study was to evaluate the pressure gradient across the oxygenator and the gas exchange performance within a blood flow rate (BFR) range of 1–4 L/min, typically used in clinical practice for ECMO and ECCO2R.
Insight Into ECMO, Mortality and ARDS: A Nationwide Analysis of 45,647 ECMO Runs
ARDS is a severe disease with a high mortality rate despite ECLS therapy. Although endpoints and timing of the evaluations differed from those of the CESAR and EOLIA studies and the Extracorporeal Life Support Organization (ELSO) Registry, the reported mortality in these studies was lower than in the present analysis. Further prospective analyses are necessary to evaluate outcomes in ECMO therapy at the centre volume level.