Cardiopulmonary Bypass, Hemolysis, and Nitroprusside-Induced Cyanide Production
Cyanide toxicity is a complication of sodium nitroprusside administration. Cardiac surgery may increase the risk of cyanide toxicity, because hemolysis during cardiopulmonary bypass (CPB) may catalyze the release of free cyanide from sodium nitroprusside.
Desflurane Preconditioning in Coronary Artery Bypass Graft Surgery: A Double-Blinded, Randomised and Placebo-Controlled Study
It was hypothesized that desflurane preconditioning would decrease postoperative release of troponin I and brain natriuretic peptide (NT-proBNP).
Red Blood Cell Transfusions and the Risk of ARDS Among Critically Ill: A Cohort Study
Recent data indicate that transfusion of packed red cells (pRBCs) may increase the risk for the development of Acute Respiratory Distress Syndrome (ARDS) in critically ill patients. Uncertainty remains regarding the strength of this relationship.
Pharmacological Prevention of the Deleterious Effects of Cardiopulmonary Bypass
This study was designed to determine if ketoconazole or indomethacin could reduce the adverse effects of extracorporeal circulation.
Perioperative Blood Transfusion and Blood Conservation in Cardiac Surgery: The Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists Clinical Practice Guideline
careful review of available evidence can provide guidelines to allocate this valuable resource and improve patient outcomes.
10 Hemoglobin Test Result Variability and Cost Analysis of Eight Different Analyzers During Open Heart Surgery
The purpose of this study was to compare the variation in hemoglobin (Hgb) values among various point-of-care (POC) analyzers available on the market.
Neuroprotective Effect of Mild Hypothermia in Patients Undergoing Coronary Artery Surgery With Cardiopulmonary Bypass: Five-Year Follow-up of a Randomized Trial
In a randomized trial of 223 patients undergoing coronary artery surgery with cardiopulmonary bypass, we have reported a neuroprotective effect of mild hypothermia. To determine whether the beneficial effect of mild hypothermia was long-lasting, we repeated the psychometric tests in 131 patients after 5 years.
Impact of Sonoclot Hemostasis Analysis After Cardiopulmonary Bypass on Postoperative Hemorrhage in Cardiac Surgery
In this study, we used a modified Sonoclot assay, using cuvettes with a glass bead activator containing heparinase, and compared the Sonoclot data before and after cardiopulmonary bypass (CPB) to assess the usefulness in predicting postoperative hemorrhage.
Bivalirudin Anticoagulation for Cardiopulmonary Bypass
We present the case of a patient with heparin hypersensitivity who was anticoagulated with bivalirudin during cardiopulmonary bypass for coronary artery bypass grafting.
Transfusion-Free Cardiac Reoperation in an 11-kg Jehovah’s Witness Child by Use of a Minimized Cardiopulmonary Bypass Circuit
Herein, we describe the design of a perfusion system for a complex cardiovascular reoperation in an 11-kg Jehovah's Witness patient. The goal of safe, transfusion-free surgery was achieved chiefly by minimizing the priming volume of the cardiopulmonary bypass circuit to 200 mL while providing adequate flow and standard safety features.
Management of Air Embolism During HeartMate XVE Exchange
We present a case in which a 45-year-old man supported by a HeartMate(R) XVE left ventricular assist device required a pump exchange due to failure of the device motor.
Body Perfusion in Surgery of the Aortic Arch
We propose a new cannulation and perfusion technique for aortic arch surgery, in order to achieve continuous antegrade total-body perfusion under moderate hypothermia.