Increased Accuracy in Heparin and Protamine Administration Decreases Bleeding: A Pilot Study
The purpose of the study was to evaluate whether a heparin–protamine titration system, Hemochron RxDx, could reduce postoperative bleeding and blood transfusion.
Optimizing Circuit Design Using a Remote-Mounted Perfusion System
In this study, using Terumo’s System 1 Advanced Heart-Lung machine, all the pump heads were remotely mounted off the pump base closer to the patient and to all the pump components.
Platelet Hyperreactivity in Response to On- and Off-pump Coronary Artery Bypass Grafting
The aim of this study was to evaluate the changes in platelet reactivity in response to cardiac surgery, both OPCAB and CABG.
Use of a Thrombelastograph Platelet Mapping Assay for Diagnosis of Clopidogrel Resistance: A Case Report
In an attempt to increase ADP inhibition, the ADP antagonist was changed to ticlopidine. Further testing was confounded by the presence of abciximab; however, the patient has remained free of cardiac events.
Post-Arterial Filter Gaseous Microemboli Activity of Five Integral Cardiotomy Reservoirs During Venting: An In Vitro Study
During a previously published study on gaseous microemboli (GMEs) and perfusionist interventions, it was noted that emboli could be detected after the arterial filter when blood/air challenges entered the membrane oxygenator’s integral cardiotomy.
An 11-Year, Single-institution Analysis of Intra-aortic Balloon Pump Use in Cardiac Surgery
The primary objective of this study was to analyze perioperative intra-aortic balloon pump (IABP) insertion in patients undergoing cardiac surgery in the authors' institution from 1995 to 2005 and to propose an explanation for changes in use over this period.
Single Center Experience With a Low Volume Priming Cardiopulmonary Bypass Circuit for Preventing Blood Transfusion in Infants and Small Children
This retrospective study analyzed the current practice of blood transfusion-free open-heart surgery in 536 children weighing 5-20 kg undergoing surgery between 2004 and 2007.
Can Pulsatile Cardiopulmonary Bypass Prevent Perioperative Renal Dysfunction during Myocardial Revascularization in Elderly Patients?
Since older subjects have a higher risk of acute renal failure, we have extended our study to evaluate the specific impact of pulsatile CPB on the perioperative renal function in elderly patients.
Effects of Haemofiltration and Mannitol Treatment on Cardiopulmonary-Bypass Induced Immunosuppression
The aim of our present study was to evaluate the ability of antioxidant therapy with mannitol or haemofiltration during CPB to modulate this immunosuppression after CPB.
Integrated Model of Endothelial NO Regulation and Systemic Circulation for the Comparison Between Pulsatile and Continuous Perfusion
Many experimental studies concerning nitric oxide (NO) release from endothelium and its vasodilative action are available in the literature, but no analytical description or modeling of these phenomena can be found.
Body Perfusion During Adult Cardiopulmonary Bypass is Improved by Pulsatile Flow With Intra-Aortic Balloon Pump
To evaluate if the use of an intra-aortic balloon pump (IABP) during cardioplegic arrest improves body perfusion.
Tranexamic Acid and Aprotinin in Low and Intermediate-Risk Cardiac Surgery: A Non-Sponsored, Double-Blind, Randomised, Placebo-Controlled Trial
We wanted to compare the effectiveness of tranexamic acid versus aprotinin in reducing postoperative blood loss and transfusion requirements in the patient group representing the majority of cardiac surgery patients: low- and intermediate-risk patients.