Change in Heparin Potency and Effects on the Activated Clotting Time in Children Undergoing Cardiopulmonary Bypass
In this investigation we provide objective evidence that the level of anticoagulation after the initial pre-CPB heparin bolus as assessed by the ACT is significantly less with use of the new heparin.
Long-term Mechanical Circulatory Support (Destination Therapy): On Track to Compete with Heart Transplantation?
Average 2-year survival after cardiac transplantation is approximately 80%.
Cerebral Microbleeds After Use of Extracorporeal Membrane Oxygenation in Children
We reviewed MRI scans for all vascular neurology consultations in children treated with ECMO at an academic medical center over a 5-year period.
Characterizing the Impact of Minor Cannula Design Modification
The aim of this study was to investigate the effect of the internal diameter of the extracorporeal connecting tube of venous cannulas on flow rate (Q), pressure drop (delta P), and cannula resistance (delta P/Q²) values, using a computer assisted test bench.
Device Thrombogenicity Emulation: A Novel Method for Optimizing Mechanical Circulatory Support Device Thromboresistance
To address the unmet need for enhancing the thromboresistance of these devices to extend their long term use, we developed a universal predictive methodology entitled Device Thrombogenicity Emulation (DTE) that facilitates optimizing the thrombogenic performance of any MCS device--ideally to a level that may obviate the need for mandatory anticoagulation.
Extracorporeal Membrane Oxygenation Cannulation Trends for Pediatric Respiratory Failure and Central Nervous System Injury
Guidelines regarding arterial cannula site and cannula site-specific risks of central nervous system (CNS) injury for pediatric patients requiring extracorporeal membrane oxygenation (ECMO)support are lacking.
Transesophageal Echocardiography Guided Cannulation for Peripheral Cardiopulmonary Bypass During Robotic Cardiac Surgery
The purpose of this study was to evaluate TEE guided cannulation for peripheral CPB during robotic cardiac surgery.
Prolonged Heparin-Free Extra Corporeal Membrane Oxygenation in Multiple Injured Acute Respiratory Distress Syndrome Patients with Traumatic Brain Injury
Based on our experience, we recommend the use of heparin-free ECMO in multiple injured patients with pulmonary failure that is not successfully controlled by lung-protective ventilation even if severe TBI is present.
Risks vs. Benefits of the Off-Label Use of Recombinant Factor VIIa in the Cardiac Arena (EP Video)
Alicia Sievert discusses the risks and benefits of off-label use of Recombinant Factor VIIa (23:00 minutes).
What You Need to Know About Novel Anticoagulants, PCCs (Prothrombin Complex Concentrates) and Human Fibrogen Concentrates (EP Video)
Dr. Suzanne Bakdash discusses novel anticoagulants and complex fibrogen concentrates (35:30 minutes).
An Educational Training Simulator for Advanced Perfusion Techniques Using a High-Fidelity Virtual Patient Model
This simulation model is a useful educational tool to learn the recognition and management skills of extracorporeal circulation.
Data Collection and Interpretation in Blood Management (EP Video)
Dr. Mark Popovsky discusses the collection and interpretation of data in a blood management program (43:34 minutes).