Anticoagulation and Bleeding in Patients with Ventricular Assist Devices: Walking the Tightrope
A left ventricular assist device (LVAD) is a lifesaving therapy for end-stage heart failure, but it is associated with major complications such as bleeding and thrombosis.
Low Incidence of Bleeding-Related Morbidity with Left Ventricular Assist Device Implantation in the Current Era
The potential to reduce bleeding reduces invasiveness of LVAD surgery, reduces allosensitization, may improve outcomes, and may increase mainstream acceptability of LVADs as definitive therapy for heart failure.
Mock Circulation Simulation of Extracorporeal Membrane Oxygenation Support for Systemic Ventricular Failure in an Infant: The Effect of Atrial Septostomy
This study demonstrates that a mock circulation can be used to investigate the size of an ASD necessary to effect sufficient clinical improvement in a two-ventricle infant on ECMO.
Acute Hyponatremia after Cardioplegia by Histidine-Tryptophane-Ketoglutarate–A Retrospective Study
Acute hyponatremia during cardioplegia with HTK solution is isotonic and should probably not be corrected without presence of hypotonicity as confirmed by measurement of serum osmolality.
Preservation of Myocardium During Coronary Artery Bypass Surgery
In the present review article on myocardial protection in contemporary coronary artery bypass surgery, we attempt to elucidate the clinical problems, summarize the outcomes of selected phase III trials, and introduce new perspectives.
Cost-Effectiveness of the Implantable HeartMate II Left Ventricular Assist Device for Patients Awaiting Heart Transplantation
Although HeartMate II LVAD implantation significantly increases survival compared with conventional medical management, it does not provide good value for the money spent according to established thresholds of cost-effectiveness in the UK.
Hydrogen as Additive of HTK Solution Fortifies Myocardial Preservation in Grafts with Prolonged Cold Ischemia
Hydrogen as additive of HTK solution fortifies HTK's preservation efficacy for cardiac grafts subjected to prolonged cold ischemia by inhibiting cold ischemia-induced up-regulation of oxidative stress, inflammation mediators, and apoptosis.
Reduction of Chronic Graft Injury with a New HTK-Based Preservation Solution in a Murine Heart Transplantation Model
The new HTK-based solution reduces the chronic isograft injury.
Failure Mode Effects Analysis (EP Video)
Jim Reagor discusses failure mode effects analysis to enhance perfusion safety (20:13 minutes).
A Roadmap for Bridging the Quality Chasm in Cardiac Surgery (EP Video)
Dr. Richard Prager presents a roadmap for bridging the disparity in quality outcomes (56:25 minutes).
The Effects of Sevoflurane Anesthesia and Cardiopulmonary Bypass on Renal Function in Cyanotic and Acyanotic Children Undergoing Cardiac Surgery
We have concluded that renal function was not affected during open heart surgery with sevoflurane anesthesia, in both cyanotic and acyanotic children.
Right Ventricular Dysfunction Following Continuous Flow Left Ventricular Assist Device Placement in 51 Patients: Predicators and Outcomes
The adjustment of septal deviation through gradual increase of the LVAD flow can prevent the acute RV dysfunction following LVAD placement.