Hypertonic Solution Decreases Extravascular Lung Water in Cardiac Patients Undergoing Cardiopulmonary Bypass Surgery
To test the hypothesis that the infusion of hypertonic solution would decrease extravascular lung water postoperatively and thus improve pulmonary function.
Contribution of Endogenous Bradykinin to Fibrinolysis, Inflammation, and Blood Product Transfusion Following Cardiac Surgery: A Randomized Clinical Trial
This study tested the hypothesis that endogenous bradykinin contributes to the fibrinolytic and inflammatory response to CPB and that bradykinin B(2) receptor antagonism reduces fibrinolysis, inflammation, and subsequent transfusion requirements.
Strategic and Operational Aspects of a Transfusion-Free Neonatal Arterial Switch Operation
At our institution, a 3.5 kg neonate, born to a family of Jehovah's Witnesses and postnatally diagnosed with dextro-transposition of the great arteries (d-TGA) and a small muscular ventricular septal defect, underwent a successful arterial switch operation without blood or platelet transfusion.
Pulmonary Perfusion with Oxygenated Blood or Custodiol HTK Solution during Cardiac Surgery for Postoperative Pulmonary Function in COPD Patients
The Pulmonary Protection Trial (PP-Trial) randomizes 90 patients undergoing CPB-dependent cardiac surgery to evaluate whether pulmonary perfusion with oxygenated blood or custodiol HTK solution reduces postoperative pulmonary dysfunction in COPD patients.
Clinical Outcome of the PAS-Port Proximal Anastomosis System in Off-Pump Coronary Artery Bypass Grafting in 201 Patients
The objective of the present study was to evaluate the clinical outcome of the PAS-Port® Proximal Anastomosis System.
Effects of Circuit Residual Volume Salvage Reinfusion on the Postoperative Clinical Outcome for Pediatric Patients Undergoing Cardiac Surgery
This study aimed to evaluate the effects of washed cardiopulmonary (CPB) circuit residual blood reinfusion on the postoperative clinical outcome for pediatric patients undergoing cardiac surgery.
Remote Ischemic Preconditioning: The Surgeon’s Perspective
Remote ischemic preconditioning, with the use of brief episodes of ischemia and reperfusion of vascular territories remote from the heart, has been shown convincingly to decrease myocardial injury.
Effects of 60 Minutes of Hyperoxia Followed by Normoxia before Coronary Artery Bypass Grafting on the Inflammatory Response Profile and Myocardial Injury
Pre-treatment by 60 minutes of hyperoxia did not reduce postoperative leak of cTn T in patients undergoing coronary artery bypass surgery.
Late Pharmacologic Conditioning with Volatile Anesthetics after Cardiac Surgery
The aim of this randomized controlled trial was to investigate whether volatile anesthetics used for postoperative sedation have any beneficial effects on myocardial injury in cardiac surgery patients after on-pump valve replacement.
Mechanism of Action of Anti-Thrombin (EP Video)
Grifols provides a product overview of Thrombate: indications, dosing and administration and how it is supplied (8:27 minutes).
Intraoperative Flowmetry Provides Quality Assurance during Coronary Artery Bypass Grafting Surgery (EP Video)
Coupled with a flow sensor on the heart lung machine to verify delivered cardioplegia flow, flow measurements during CABG provide a dual measure of quality assurance (9:57 minutes).
Perioperative Blood Management during Cardiopulmonary Bypass (EP Video)
The management of perioperative blood during CPB can complement or negate other strategies to improve biocompatibility. While not possible on every case, simple techniques and circuit designs can give perfusionists options to manage perioperative blood. This presentation will discuss those options and share clinical experience using them (10:22 minutes).