Prospective Clinical Trial on dosage Optimizing of Tranexamic Acid in Non-Emergency Cardiac Surgery Procedures
After withdrawal of aprotinin in 2008 only tranexamic acid (TxA, Cyclocapron, Pfitzer, Germany) remains available as antihyperfibrinolytic agent in Europe.
How Effective are Injection Treatments for Lateral Epicondylitis
We compared the effectiveness, after 3 months, of a single injection of platelet-rich plasma (PRP), glucocorticoid (GC), or saline in reducing pain in lateral epicondylitis.
Comparison of the Effects of Albumin 5%, Hydroxyethyl Starch 130/0.4 6%, and Ringer’s Lactate on Blood Loss and Coagulation after Cardiac Surgery
We randomly assigned 240 patients undergoing elective cardiac surgery to receive up to 50 ml kg-1 day-1 of either HA, HES, or Ringer's lactate (RL) as the main infusion fluid perioperatively.
Implementation of an Institutional Protocol for Rational Use of Blood Products and Its Impact on Postoperative of Coronary Artery Bypass Graft Surgery
We evaluated the short-term effects of implementation of a protocol for the rational use of blood products in the perioperative period of cardiac surgery.
Achilles Tendinopathy Management: A Pilot Randomized Controlled Trial Comparing Platelet-Rich Plasma Injection with an Eccentric Loading Programme
We conducted a pilot randomized controlled trial to evaluate the feasibility of conducting a larger trial to evaluate the difference in Victorian Institute of Sports Assessment-Achilles (VISA-A) scores at six months between patients with Achilles tendinopathy treated with a platelet-rich plasma (PRP) injection compared with an eccentric loading programme.
Cardiac Surgery in a Patient with Severe Thrombocytopenia: How Low is Too Low
We report a case of severe thrombocytopenia (19 × 10 9 /L) where coronary artery bypass grafting was performed with minimal blood loss post-operatively, discuss the patient's management and provide insights while dealing with such patients.
Combined Treatment of Ulinastatin and Tranexamic Acid Provides Beneficial Effects by Inhibiting Inflammatory and Fibrinolytic Response in Patients Undergoing Heart Valve Replacement Surgery
We investigated the effect of ulinastatin and tranexamic acid administered alone or in combination on inflammatory cytokines and fibrinolytic system in patients undergoing heart valve replacement surgery during cardiopulmonary bypass (CPB).
Population Pharmacokinetics of Tranexamic Acid in Adults Undergoing Cardiac Surgery with Cardiopulmonary Bypass
The objectives of this study were to investigate the population pharmacokinetics (PK) of tranexamic acid (TA) given with either low- or high-dose continuous infusion schemes in adult cardiac surgery patients during cardiopulmonary bypass (CPB).
The Biomechanics and Histological Effects of Platelet-Rich Plasma on Fracture Healing
Platelet-rich plasma (PRP) includes growth factors and proteins that accelerate and stimulate bone regeneration and tissue recovery. The aim of this study was to evaluate the effects of PRP on fracture healing in terms of biomechanics and histology.
Comparison of Two Doses of Tranexamic Acid in Adults Undergoing Cardiac Surgery with Cardiopulmonary Bypass
The optimal dose of tranexamic acid (TA) is still an issue. The authors compared two doses of TA during cardiac surgery in a multicenter, double-blinded, randomized study.
Comparison of Epsilon Aminocaproic Acid and Tranexamic Acid in Thoracic Aortic Surgery: Clinical Efficacy and Safety
This study evaluates the efficacy and safety of tranexamic acid (TXA) versus epsilon aminocaproic acid (EACA) in patients undergoing thoracic aortic surgery.
Autologous Blood Derived Signaling Proteins for Tendon and Muscle Therapy in Sports Medicine Higher Concentration of Growth Factors and Cytokines in Orthokine VS in ACP
We compared 2 none-PRP techniques: ORTHOKINE (Oe) for Autologous Conditioned Serum (ACS) and ACP (Ax) for autologous plasma (AP)