American Society of ExtraCorporeal Technology: Development of Standards and Guidelines for Pediatric and Congenital Perfusion Practice (2019)
The Standards and Guidelines for Pediatric and Congenital Perfusion Practice is an essential tool for pediatric perfusionists and serves as the backbone for institutionally based protocols, promotes improved decision-making, and identifies opportunities for future research and collaboration with other disciplines.
Goal-Directed Perfusion to Reduce Acute Kidney Injury after Paediatric Cardiac Surgery (GDP-Akip): Study Protocol for A Prospective Randomised Controlled Trial
In total, 166 paediatric patients undergoing cardiac surgery will be randomly allocated to the GDP group or control group. Patients in the GDP arm will be treated with a GDP strategy during CPB aimed to maintain DO2i at ≥360 mL/min/m2 .
Use of Extracorporeal Membrane Oxygenation After Congenital Heart Disease Repair: A Systematic Review and Meta-Analysis
There is an overall high in-hospital mortality of 56.8% in postoperative CHD patients on ECMO. Bleeding is the most common complication during ECMO running with an incidence of 47.1%.
Mechanisms of Perioperative Brain Damage in Children with Congenital Heart Disease.
This study analyses the forms of structural and functional brain damage in the early postoperative period, along with the recent evolution of research on its contributing factors.
The Relationships of Cerebral and Somatic Oxygen Saturation with Physiological Parameters in Pediatric Cardiac Surgery with Cardiopulmonary Bypass: Analysis Using the Random-Effects Model.
Through the whole surgical period, ScO2 correlated strongly with mean blood pressure regardless of the physiological type. the physiological parameters affecting ScO2 and SrO2 were rather different. Accordingly, the significance of monitoring of cerebral and somatic tissue oxygen saturation in pediatric cardiac surgery should be further evaluated.
Impact of Haemolysis On Vancomycin Disposition in A Full-Term Neonate Treated with Extracorporeal Membrane Oxygenation.
Vancomycin elimination may be severely prolonged due to ECMO-induced haemolysis and acute kidney injury, while hypothesis of direct increase of vancomycin levels by releasing the drug from blood cells during haemolysis has been disproved.
Characteristics of Pediatric Extracorporeal Membrane Oxygenation Programs in the United States and Canada
The majority of pediatric ECMO centers have adopted the infrastructure recommendations from the Extracorporeal Life Support Organization. However, there remains broad variability of practice characteristics and organizational infrastructure for pediatric ECMO centers across the United States and Canada.
COVID-19 Testing, Surgical Prioritization, and Reactivation in a Congenital Cardiac Surgery Program
In summary, our institutional experience demonstrates that the implementation of universal COVID-19 screening, surgical prioritization, and eventual reactivation is feasible for congenital cardiac surgery programs.
Combined Use of Rotational Thromboelastometry (Rotem) and Platelet Impedance Aggregometry (Multiplate Analyzer) in Cyanotic and Acyanotic Infants and Children Undergoing Cardiac Surgery With Cardiopulmonary Bypass: Subgroup Analysis of a Randomized Clinical Trial
This study showed that Rotem, but not Multiplate results, were associated with platelet transfusion in pediatric cardiac surgery with no intake of platelet inhibitors. The usefulness of combining these tests in platelet transfusion decision-making needs to be evaluated in larger populations.
Impact of Miniaturized Cardiopulmonary Bypass Circuits on Ultrafiltration During Congenital Heart Surgery
The miniaturized CPB system could decrease the usage of UF. Good results were achieved in children who did not use UF based on the miniaturized CPB circuit system during congenital heart surgery.
Biomarkers as Predictors of Renal Damage in Neonates Undergoing Cardiac Surgery
In our study, biomarkers did not show any correlation with the appearance of AKI.
A Randomized Controlled Trial Comparing Controlled Reoxygenation and Standard Cardiopulmonary Bypass in Paediatric Cardiac Surgery
Controlled reoxygenation (normoxic) CPB is safe but with no evidence of a clinical advantage over hyperoxic CPB.