Chronic Stable Ischaemia and Myocyte Damage During Beating Heart Surgery
OBJECTIVES: Many patients with coronary artery disease demonstrate chronic resting ischaemic myocardial dysfunction. We have investigated whether this ischaemia influences the myocardial […]
Ratio of Total to LDL Cholesterol Is Best Predictor Of Coronary Heart Disease
Current guidelines for lipid management may misclassify subjects with both high and low levels of high density lipoprotein cholesterol (HDL-C) and low […]
Surgical Repair of Acute Type A Aortic Dissection: Continuous Pulmonary Perfusion Prevents Lung Injury in a Pilot Study
Objective: Postoperative respiratory failure is a frequent and serious complication in patients with type A acute aortic dissection operated on with deep […]
Importance of Blood Pressure Regulation in Maintaining Adequate Tissue Perfusion
Abstract: Patients undergoing surgery with the aid of cardiopulmonary bypass(CPB)have an incidence of end-organ dysfunction, caused by embolization, regional hypoperfusion, or some […]
Mitral Valve Replacement Still Problematic in Young Children
WESTPORT, CT (Reuters Health) – With the advent of mechanical prostheses, valve failure is no longer a problem after mitral valve replacement […]
Myocardial Protection with Oxygenated Esmolol Cardioplegia During Prolonged Normothermic Ischemia in the Rat
Objective: We previously showed that arrest with multidose infusions of high-dose (1 mmol/L) esmolol (an ultra-short-acting ß-blocker) in oxygenated Krebs-Henseleit buffer (esmolol […]
Should Standard On-Pump Protamine Dosing Formulas Be Recalculated for Off-Pump Coronary Artery Bypass Grafting?
Background: Since 1994 at the authors’ institution, approximately 9000 cardiac surgical procedures were performed using activated clotting time (ACT)-monitored heparin anticoagulation for […]
Meta-Analysis on the Effect of Off-Pump Coronary Bypass Surgery
Objective: To assess the effect of conventional coronary artery bypass surgery (CABG) compared to the off-pump procedure (OPCAB). Methods: Based on randomised […]
Transfusion Protocols for Pediatric Cardiac Patients
OBJECTIVES: Low-hematocrit bypass is one technique used to prevent allogeneic transfusion during cardiopulmonary bypass. The purpose of this study is to determine […]
Platelet-Derived Growth Factors Enhance Proliferation of Human Stromal Stem Cells
Studies on new procedures for bone reconstruction suggest that autologous cells seeded on a resorbable scaffold can improve the treatment of bone […]
High-grade Stenosis of Proximal LAD Responds Better to CABG Than Stenting
In patients with high-grade stenosis in the proximal left anterior descending coronary artery (LAD), outcomes after coronary artery bypass grafting (CABG) are […]
Extreme Hemodilution During CABG Linked to Kidney Damage
NEW YORK (Reuters Health) – Nadir hematocrit caused by hemodilution during coronary artery bypass graft (CABG) surgery appears to be associated with […]