Evaluation of Myocardial Metabolism With Microdialysis After Protection With Cold Blood or Cold Crystalloid Cardioplegia. A Porcine Model
In an acute porcine model we examined two standard cardioplegic methods. Myocardial microdialysis was used to investigate the metabolism during cardioplegic arrest and in the reperfusion period.
Randomized Controlled Trial of Pericardial Blood Processing With a Cell-Saving Device on Neurologic Markers in Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery
The present study tested the hypothesis that processing of pericardial shed blood with a cell-saving device during cardiopulmonary bypass would significantly decrease serum levels of protein S100B, and improve brain oxygen saturation and neurologic outcome, all markers of brain injury in elderly patients.
Intraaortic Balloon Pumping During Cardioplegic Arrest Preserves Lung Function in Patients With Chronic Obstructive Pulmonary Disease
We evaluated differences in lung function of patients with COPD undergoing preoperative intraaortic balloon pumping (IABP), between linear flow during cardiopulmonary bypass (IABP-off) and maintenance of pulsatile flow (IABP-on at automatic 80 bpm) during cardioplegic arrest.
Intermittent Pressure Augmentation During Retrograde Cerebral Perfusion Under Moderate Hypothermia Provides Adequate Neuroprotection: An Experimental Study
For cerebral protection during aortic surgery, we introduced a novel retrograde cerebral perfusion method with intermittent pressure augmentation.
Cardiopulmonary Bypass Management and Neurologic Outcomes: An Evidence-Based Appraisal of Current Practices
Neurologic complications after cardiac surgery are of growing importance for an aging surgical population. In this review, we provide a critical appraisal of the impact of current cardiopulmonary bypass (CPB) management strategies on neurologic complications.
The Hemodynamic Effects of Methylene Blue When Administered at the Onset of Cardiopulmonary Bypass
In this study we examined the hemodynamic effects of methylene blue (MB), an inhibitor of guanylate cyclase, administered during cardiopulmonary bypass (CPB) to patients taking angiotensin-converting enzyme inhibitors.
A Novel Antidote-Controlled Anticoagulant Reduces Thrombin Generation and Inflammation and Improves Cardiac Function in Cardiopulmonary Bypass Surgery
Here we demonstrate that an anticoagulant aptamer-antidote pair targeting factor IXa can replace heparin and protamine in a porcine CPB model and also limit the adverse effects on thrombin generation, inflammation, and cardiac physiology associated with heparin and protamine use.
Factors Predicting Loss and Gain of Red Cell Volume in Cardiac Surgery Patients
This study has been designed to analyse what peri-operative variables may be associated with loss or gain in RCV due to bleeding or transfusion.
International Perfusion Journal Vol. 2 No. 6
Table of Contents: IntroductionReview of Empty Venous Line Technique with Gerard Meyers Empty Venous Line Technique, a Supporting View John Brooks, Chief […]
Whole-Body Perfusion under Moderate-Degree Hypothermia during Aortic Arch Repair
We report our operative and postoperative outcomes for cases of aortic arch replacement using whole-body perfusion during aortic reconstruction under 28 degrees C moderate hypothermia.
Neurocognitive Outcomes in Off-Pump Versus On-Pump Bypass Surgery: A Randomized Controlled Trial
Cognitive difficulties have been reported after coronary artery bypass graft surgery using cardiopulmonary bypass.
Hemodynamic Effects of Cardiotomy Suction Blood
We investigated the effect of cardiotomy suction blood on systemic vascular resistance in vivo and whether cell-saver processing of suction blood affects the vascular response.