Argatroban as a Aubstitute of Heparin During Cardiopulmonary Bypass: A Safe Alternative?
The objective of this communication is to report our recent experience with this agent during cardiopulmonary bypass (CPB) and to review the cases previously published in order to better define indications, dosage, monitoring and limitations in cardiac surgery patients.
Open Heart Surgery in Patients With Sickle Cell Hemoglobinopathy
The aim of this study was to review retrospectively the perioperative results of patients undergoing cardiac surgery at our institution.
Bivalirudin Anticoagulation During Cardiac Surgery: A Single-Center Experience in 141 Patients
Here, we report our single-center experience with bivalirudin anticoagulation in "on-pump" and "off-pump" cardiac surgery in a large number of patients with and without heparin antibodies.
Evaluation of the Efficacy of Platelet-Rich Plasma in Delivering BMSCs Into 3D Porous Scaffolds
The purpose of this study was to evaluate the efficacy of PRP in delivering bone marrow stromal cells (BMSCs) into 3D porous scaffolds in comparison with platelet-poor plasma (PPP) and Dulbecco's modified Eagle's medium (DMEM).
A New De-Airing Technique that Reduces Systemic Microemboli During Open Surgery: A Prospective Controlled Study
We have evaluated a new technique of cardiac de-airing that is aimed at a) minimizing air from entering into the pulmonary veins by opening both pleurae and allowing lungs to collapse and b) flushing out residual air from the lungs by staged cardiac filling and lung ventilation.
The Effects of Normoxic Versus Hyperoxic Cardiopulmonary Bypass on Oxidative Stress and Inflammatory Response in Cyanotic Pediatric Patients Undergoing Open Cardiac Surgery: A Randomized Controlled Trial
This study investigates the effects of controlled reoxygenation cardiopulmonary bypass on oxidative stress, inflammatory response, and organ function in children undergoing repair of cyanotic congenital heart defects.
Bicarbonate-Buffered Ultrafiltration During Pediatric Cardiac Surgery Prevents Electrolyte and Acid-Base Balance Disturbances
We tested the hypothesis of whether bicarbonate-buffered hemofiltration of the priming solution minimizes electrolyte and acid-base disturbances during the initiation of cardiopulmonary bypass and whether bicarbonate-buffered hemofiltration performed during cardiopulmonary bypass could reduce cytokine levels.
Myocardial Preservation: An Opportunity for Improvement (Video)
Aaron Hill, one of the living lengends in the perfusion industry, discusses current trends in myocardial protection (40 minutes).
Triboelectric Charging and Dissipation Characteristics of the Maquet Quadrox-D Membrane Oxygenator
We evaluated the ability of the Quadrox-D (Maquet) to effectively remove the electrostatic charge accumulation, with and without a heater/cooler connection (H/C).
Trends and Emerging Technologies in Extracorporeal Life Support: Results of the 2006 ECLS Survey
This article presents our 2006 ECLS survey results and discusses emerging technologies and management topics new to the ECLS arena.
Anti-Infl ammatory Effect of Aprotinin: A Meta-Analysis
. In this study, we investigated the published data on aprotinin’s effect on acute phase protein and cytokine levels in cardiac surgery patients.