Argatroban as a Aubstitute of Heparin During Cardiopulmonary Bypass: A Safe Alternative?
The objective of this communication is to report our recent experience with this agent during cardiopulmonary bypass (CPB) and to review the cases previously published in order to better define indications, dosage, monitoring and limitations in cardiac surgery patients.
Open Heart Surgery in Patients With Sickle Cell Hemoglobinopathy
The aim of this study was to review retrospectively the perioperative results of patients undergoing cardiac surgery at our institution.
Bicarbonate-Buffered Ultrafiltration During Pediatric Cardiac Surgery Prevents Electrolyte and Acid-Base Balance Disturbances
We tested the hypothesis of whether bicarbonate-buffered hemofiltration of the priming solution minimizes electrolyte and acid-base disturbances during the initiation of cardiopulmonary bypass and whether bicarbonate-buffered hemofiltration performed during cardiopulmonary bypass could reduce cytokine levels.
Bivalirudin Anticoagulation During Cardiac Surgery: A Single-Center Experience in 141 Patients
Here, we report our single-center experience with bivalirudin anticoagulation in "on-pump" and "off-pump" cardiac surgery in a large number of patients with and without heparin antibodies.
Evaluation of the Efficacy of Platelet-Rich Plasma in Delivering BMSCs Into 3D Porous Scaffolds
The purpose of this study was to evaluate the efficacy of PRP in delivering bone marrow stromal cells (BMSCs) into 3D porous scaffolds in comparison with platelet-poor plasma (PPP) and Dulbecco's modified Eagle's medium (DMEM).
A New De-Airing Technique that Reduces Systemic Microemboli During Open Surgery: A Prospective Controlled Study
We have evaluated a new technique of cardiac de-airing that is aimed at a) minimizing air from entering into the pulmonary veins by opening both pleurae and allowing lungs to collapse and b) flushing out residual air from the lungs by staged cardiac filling and lung ventilation.
The Effects of Normoxic Versus Hyperoxic Cardiopulmonary Bypass on Oxidative Stress and Inflammatory Response in Cyanotic Pediatric Patients Undergoing Open Cardiac Surgery: A Randomized Controlled Trial
This study investigates the effects of controlled reoxygenation cardiopulmonary bypass on oxidative stress, inflammatory response, and organ function in children undergoing repair of cyanotic congenital heart defects.
Myocardial Preservation: An Opportunity for Improvement (Video)
Aaron Hill, one of the living lengends in the perfusion industry, discusses current trends in myocardial protection (40 minutes).
Carotid Artery Diameter, Plaque Morphology, and Hematocrit, in Addition to Percentage Stenosis, Predict Reduced Cerebral Perfusion Pressure during Cardiopulmonary Bypass: A Mathematical Model
A mathematical model using finite element analysis was created to model the carotid artery vessel and its stenotic plaque.
Influence of Cardiopulmonary Bypass on the Interaction of Recombinant Factor VIIa with Activated Platelets
Recombinant factor VIIa (rFVIIa) interacts preferentially with coated platelets characterized by a high exposure of phosphatidyl serine (PS), FV, FVIII, FIX, and FX binding, and fibrinogen.
Australian and New Zealand Perfusion Survey: Management and Procedure
In this report, we will discuss management and procedural aspects of perfusion practice. This report allows us to compare and contrast recent trends and changes in perfusion with historic practices.