The Kinetics of Cardiopulmonary Bypass: A Dual-platform Proteomics Study of Plasma Biomarkers in Pediatric Patients Undergoing Cardiopulmonary Bypass
This study was designed to investigate the expression kinetics and patterns of plasma biomarkers throughout the pediatric cardiopulmonary bypass (CPB) procedure to help predict those patients most at risk for complications.
Haematocrit is Invalid for Estimating Red Cell Volume: A Prospective Study in Male Volunteers
Although haematocrit and haemoglobin value are concentrations, they are commonly used to guide clinical decisions involving red cell and plasma volumes. A study challenging this convention systematically co-determined and compared these measures.
Anatomy, Mechanics, and Pathophysiology of the Mitral Annulus
This review discusses the role of annular dysfunction in the pathogenesis of these disorders.
Multichannel Near Infrared Spectroscopy Indicates Regional Variations in Cerebral Autoregulation in Infants Supported on Extracorporeal Membrane Oxygenation
Infants on life support system (ECMO) for cardiorespiratory failure are at risk of cerebral autoregulation impairment and consequent neurological problems.
In Vivo Effects on Human Skeletal Muscle Oxygen Delivery and Metabolism of Cardiopulmonary Bypass and Perioperative Hemodilution
To investigate the in vivo effects of cardiopulmonary bypass (CPB) and perioperative hemodilution on human skeletal muscle oxygen delivery and metabolism and to determine the dilution state at which these effects arise.
Coagulopathy and Hemostatic Monitoring in Cardiac Surgery: An Update
This review describes coagulopathies occurring in cardiac surgery and the monitoring of these.
The Impact of Intraoperative Vasopressin Infusion in Complex Neonatal Cardiac Surgery
The objective of this study was to assess the impact of intraoperative vasopressin infusion on postoperative liver, renal and haemostatic function and lactate levels in neonates undergoing cardiac surgery.
Thrombelastography Change after Bridging to Left Ventricular Assist Device from Extracorporeal Membrane Oxygenation Patients
The cause of coagulopathy is seldom reported; therefore, the current prospective study was designed to compare the coagulation status between patients who received ECMO and bridged VAD thereafter.
Predicting the Limits of Cerebral Autoregulation During Cardiopulmonary Bypass
The hypothesis of this study was that real-time autoregulation monitoring using NIRS-based methods is more accurate for delineating the MAP at the lower limit of autoregulation (LLA) during CPB than empiric determinations based on age, preoperative history, and preoperative blood pressure.
Implementation of Cerebral Autoregulation into Computational Fluid Dynamics Studies of Cardiopulmonary Bypass
In this study, a mathematical model is presented to implement cerebral autoregulation into computational fluid dynamics (CFD) studies.
Nadir Hematocrit During Cardiopulmonary Bypass: End-organ Dysfunction and Mortality
To discover the effects of the lowest hematocrit during cardiopulmonary bypass on end-organ function and mortality in patients who did not receive red blood cell transfusion and to identify predictors of nadir hematocrit.
Microcirculation and Macrocirculation in Cardiac Surgical Patients
The aim of our study was to investigate the relationship between microcirculatory alterations after open cardiac surgery, macrohemodynamics, and global indices of organ perfusion.