Methylene Blue to Treat Vasoplegia due to a Severe Protamine Reaction: A Case Report
This case report describes a 57-year-old woman who after cardiac bypass experienced a severe protamine reaction with profound hypotension, which was unresponsive to volume resuscitation and vasopressor therapy.
Preliminary Evidence for Reduced Preoperative Cerebral Blood Flow Velocity as a Risk Factor for Cognitive Decline Three Months after Cardiac Surgery: An Extension Study
This extension study investigated the association between preoperative cerebral blood flow (CBF) velocity and postoperative cognitive decline (POCD) at a three-month follow-up in patients who underwent cardiac surgery.
Veno-Right Ventricular Cannulation Reduces Recirculation in Extracorporeal Membrane Oxygenation
We compared recirculation in veno-right ventricular support with that in conventional veno-venous support and its relationship with pump flow.
Perioperative Management of Antithrombotic Therapy in Cardiovascular Patients
In this article, we review some of the general principles involved with perioperative anticoagulation and discuss the perioperative management of patients taking vitamin K antagonists (VKAs), bridging regimens for anticoagulants and antiplatelet agents, and strategies for managing patients on the newer oral anticoagulants.
Thrombin Generation Assay: A New Tool to Predict and Optimize Clinical Outcome in Cardiovascular Patients?
In this review we provide a brief description of the assay and we summarize the principals of previous studies by analyzing the relationship between anticoagulant drugs and TGA.
The Science behind Percutaneous Hemodynamic Support: A Review and Comparison of Support Strategies
With these goals in mind, the scientific principles that govern hemodynamic effectiveness and myocardial protection as they pertain to acute support devices are reviewed.
Cardiopulmonary Bypass Transiently Inhibits Intraventricular Vortex Ring Formation in Patients Undergoing Coronary Artery Bypass Graft Surgery
The authors tested the hypothesis that exposure to cardiopulmonary bypass (CPB) attenuates intraventricular vortex formation time (VFT) in patients with normal preoperative LV systolic and diastolic function undergoing coronary artery bypass graft (CABG) surgery.
The Role of Procalcitonin and N-Terminal Pro-B-Type Natriuretic Peptide in Predicting Outcome after Cardiac Surgery
Determine the thresholds of procalcitonin (PCT) and N-terminal pro-B-type natriuretic peptide (Nt-pro-BNP) associated with poor prognosis after heart surgery with CPB.
Incompatible ABO-Plasma Exchange and its Impact on Patient Selection in Paediatric Cardiac Transplantation
We report the results of a decade of evolving plasma exchange experience and its impact upon patient selection.
Drug Shortages in the Perioperative Setting: Causes, Impact, and Strategies
Concern about drug shortages is growing, particularly because they can cause significant patient harm.
Antiplatelet Drugs: Mechanisms and Risks of Bleeding Following Cardiac Operations
We hypothesize that review of available evidence regarding drug-related bleeding risk, underlying mechanisms of platelet dysfunction, and variations in patient response to antiplatelet drugs will aid surgeons as they assess preoperative risk and attempt to limit perioperative bleeding.
Peripheral Extracorporeal Membrane Oxygenation System as Salvage Treatment of Patients with Refractory Cardiogenic Shock: Preliminary Outcome Evaluation
The novel Permanent Life Support (PLS; Maquet, Jostra Medizintechnik AG, Hirrlingen, Germany) as peripheral veno-arterial extracorporeal membrane oxygenation (ECMO) support system has been investigated as treatment for patients with refractory cardiogenic shock (CS).