Leiters Partners with Hibernation Therapeutics to Provide Adenocaine™ Cardioplegic Solution
Leiters, a trusted FDA-registered 503B provider of high-quality compounded sterile preparations, announced today that it has entered into a national agreement with Hibernation Therapeutics to provide a patented cardioplegic solution developed by Hibernation Therapeutics known as Adenocaine™.
Perioperative THR-184 and AKI after Cardiac Surgery
AKI after cardiac surgery is associated with mortality, prolonged hospital length of stay, use of dialysis, and subsequent CKD. We evaluated the effects of THR-184, a bone morphogenetic protein-7 agonist, in patients at high risk for AKI after cardiac surgery.
Optimizing Perioperative Blood and Coagulation Management During Cardiac Surgery
This article reviews the hemostasis disturbances in cardiac surgery with cardiopulmonary bypass and gives an overview of the most important patient blood management strategies.
Enhanced Activity by NKCC1 and Slc26a6 Mediates Acidic pH and Cl- Movement after Cardioplegia-Induced Arrest of db/db Diabetic Heart
Diabetic heart dysfunctions during cardiac surgeries have revealed several clinical problems associated with ion imbalance. However, the mechanism of ion imbalance mediated by cardioplegia and a diabetic heart is largely unclear.
Serum Lactate Poorly Predicts Central Venous Oxygen Saturation in Critically Ill Patients: a Retrospective Cohort Study
Serum lactate and central venous oxygen saturation (ScvO2) are commonly used and commonly recommended as markers of tissue oxygenation in shock states.
Conscious Sedation Versus General Anesthesia in Transcatheter Aortic Valve Replacement: A Cost and Outcome Analysis
The use of conscious sedation (CS) as compared with general anesthesia (GA) has shown better clinical outcomes for TAVR patients.
The Prognosis Impact of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Plus Cytoreductive Surgery (CRS) in Advanced Ovarian Cancer: The Meta-Analysis
Background and Objective Previous studies about the prognostic value of the HIPEC have yielded controversial results. Therefore, this study aims to assess […]
The Complexity of Atrial Fibrillation Newly Diagnosed After Ischemic Stroke and Transient Ischemic Attack: Advances and Uncertainties
Purpose of Review Atrial fibrillation is being increasingly diagnosed after ischemic stroke and transient ischemic attack (TIA). Patient characteristics, frequency and duration […]
Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure
Atrial fibrillation (AF) is commonly associated with heart failure. A bidirectional relationship exists between the two—AF exacerbates heart failure causing a significant […]
Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group
Acute kidney injury (AKI) occurs in 7% to 18% of hospitalized patients and complicates the course of 50% to 60% of those […]
Radial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery
We performed a patient-level combined analysis of randomized, controlled trials to compare radial-artery grafts and saphenous-vein grafts for coronary-artery bypass grafting (CABG).