The Bicircuit System: Innovative Perfusional Options for Surgical Treatment of the Thoracic Aorta
Surgical treatment of the thoracic aorta may become challenging when a rapid switch from left heart bypass (LHB) to cardiopulmonary bypass (CPB) is required.
Effects of Methylprednisolone and a Biocompatible Copolymer Circuit on Blood Activation During Cardiopulmonary Bypass
Cardiopulmonary bypass (CPB) induces derangements in physiology characterized by activation of blood pathways that may contribute to multiorgan dysfunction. This trial addresses the efficacy of a biocompatible surface alone and in combination with steroids in inhibiting these changes.
Coronary Revascularization Without Cardiopulmonary Bypass Versus the Conventional Approach in High-Risk Patients
High-risk patients may benefit the most from off-pump CABG. The aim of this study was to compare early and mid-term clinical outcomes after off-pump CABG with on-pump CABG in a subset of high-risk patients.
Neurologic Preservation by Na+-H+ Exchange Inhibition Prior to 90 Minutes of Hypothermic Circulatory Arrest
The effects of pretreatment with cariporide (HOE 642 Aventis Pharma, Strasbourg - Cedex, France), a Na+–H+ exchanger (NHE) blocker, were studied in a cerebral ischemia–reperfusion model of hypothermic arrest.
First Clinical Experience With the VSTENT: A Device for Direct Left Ventricle-to-Coronary Artery Bypass
Stent-based left ventricle-to-coronary artery stent (VSTENT) is a newly developed, alternative surgical revascularization procedure (VCAB). We present here our initial experience using this technique.
First Clinical Experience With the VSTENT: A Device for Direct Left Ventricle-to-Coronary Artery Bypass
Stent-based left ventricle-to-coronary artery stent (VSTENT) is a newly developed, alternative surgical revascularization procedure (VCAB). We present here our initial experience using this technique.
Cardiopulmonary Bypass Induces Significant Platelet Activation in Children Undergoing Open-Heart Surgery
To evaluate the effects of cardiopulmonary bypass (CPB) on platelet function in children undergoing open-heart surgery.
Normalization of High Pulmonary Vascular Resistance with LVAD Support in Heart Transplantation Candidates
The role of continuous flow left ventricular assist device (LVAD) support in the reduction of elevated PVR was evaluated in a series of clinical implants.
Conversion to On Pump from OPCAB is Associated With Increased Mortality: Results From a Randomized Controlled Trial
The objective of the present study was to review all conversions in the setting of a randomized controlled trial comparing CABG with or without CPB.
Angiogenesis: Protein, Gene, or Cell Therapy?
The purpose of this review is to highlight the current progress, controversies, and challenges in the development of protein, gene, and cell-based approaches for clinical therapeutic angiogenesis.
Autologous Blood Transfusion in Total Hip Arthroplasty
Combined use of the preoperative blood pooling and intra-operative recovery systems is effective for avoiding homologous blood transfusion.
Intraoperative Cell Salvage During Radical Prostatectomy: A Safe Technique for Jehovah’s Witnesses
Radical retropubic prostatectomy (RRP) is an operation historically associated with the potential for significant blood loss. Patients who refuse a blood transfusion, such as Jehovah’s witnesses, may be only offered radiation therapy as potentially curative treatment for prostate cancer because of the potential for a transfusion.