Cardiopulmonary Bypass Management and Neurologic Outcomes: An Evidence-Based Appraisal of Current Practices
Neurologic complications after cardiac surgery are of growing importance for an aging surgical population. In this review, we provide a critical appraisal of the impact of current cardiopulmonary bypass (CPB) management strategies on neurologic complications.
A Novel Antidote-Controlled Anticoagulant Reduces Thrombin Generation and Inflammation and Improves Cardiac Function in Cardiopulmonary Bypass Surgery
Here we demonstrate that an anticoagulant aptamer-antidote pair targeting factor IXa can replace heparin and protamine in a porcine CPB model and also limit the adverse effects on thrombin generation, inflammation, and cardiac physiology associated with heparin and protamine use.
Factors Predicting Loss and Gain of Red Cell Volume in Cardiac Surgery Patients
This study has been designed to analyse what peri-operative variables may be associated with loss or gain in RCV due to bleeding or transfusion.
International Perfusion Journal Vol. 2 No. 6
Table of Contents: IntroductionReview of Empty Venous Line Technique with Gerard Meyers Empty Venous Line Technique, a Supporting View John Brooks, Chief […]
Whole-Body Perfusion under Moderate-Degree Hypothermia during Aortic Arch Repair
We report our operative and postoperative outcomes for cases of aortic arch replacement using whole-body perfusion during aortic reconstruction under 28 degrees C moderate hypothermia.
Intra-Aortic Balloon Pumping in Children Undergoing Cardiac Surgery: An Update of the Liverpool Experience
We report our experience in supporting pediatric cardiac surgical patients with intra-aortic balloon pumping.
Neurocognitive Outcomes in Off-Pump Versus On-Pump Bypass Surgery: A Randomized Controlled Trial
Cognitive difficulties have been reported after coronary artery bypass graft surgery using cardiopulmonary bypass.
Hemodynamic Effects of Cardiotomy Suction Blood
We investigated the effect of cardiotomy suction blood on systemic vascular resistance in vivo and whether cell-saver processing of suction blood affects the vascular response.
Plasma Cefazolin Levels During Cardiovascular Surgery: Effects of Cardiopulmonary Bypass and Profound Hypothermic Circulatory Arrest
We sought to assess the effects of cardiopulmonary bypass and profound hypothermic circulatory arrest on plasma cefazolin levels administered for antimicrobial prophylaxis in cardiovascular surgery.
Hyperglycemia is a Marker for Poor Outcome in the Postoperative Pediatric Cardiac Patient
The goal of this study was to determine whether hyperglycemia in the postoperative period was associated with increased morbidity or mortality.
APT070 Inhibits Complement Activation During in Vitro Cardiopulmonary Bypass
We looked at the effect of APT070, an anti-complement agent, on human blood during in vitro CPB.
Myocardial Protection by Nicorandil During Open-Heart Surgery Under Cardiopulmonary Bypass
To evaluate the myocardial protective effect of nicorandil when used as an adjuvant to cold hyperkalaemic cardioplegia in open-heart surgery.