Use of the Hemobag for Modified Ultrafiltration in a Jehovah’s Witness Patient Undergoing Cardiac Surgery
This case report describes how to set up and operate the Hemobag in a Jehovah’s Witness patient undergoing cardiac surgery that requires an extracorporeal circuit.
Normothermic Cardiopulmonary Bypass and Myocardial Cardioplegic Protection for Neonatal Arterial Switch Operation
Hypothermic cardiopulmonary bypass (CPB) associated with cold myocardial protection is commonly used to perform neonatal cardiac surgery. Hypothermia is usually chosen to preserve the brain in case of failure of oxygen delivery whatever it may result from.
Automated Technique Accurately Measures Platelet Counts in “Platelet Gel” Products
A special blood concentrate known as platelet-rich plasma (PRP) can promote healing in a wide range of medical and surgical situations, but research has been limited by the lack of a universally accepted approach to measuring the platelet concentrations contained in PRP.
Preparation of Platelet-Rich Plasma as a Tissue Adhesive for Experimental Transplantation in Rabbits
Platelet-rich plasma (PRP) is an autologous substance with adhesive properties. We aimed at developing and testing the efficacy of a method for PRP preparation in rabbits.
Freeze-Dried Platelet-Rich Plasma Shows Beneficial Healing Properties in Chronic Wounds
Fresh platelet concentrates are used in many centers to treat recalcitrant wounds. To extend the therapeutic shelf-life of platelets, we analyzed the wound-healing effects of fresh-frozen and freeze-dried (FD) platelet-rich plasma (PRP) using a diabetic mouse model.
Myocardial Protection in the Failing Heart: I. Effect of Cardioplegia and the Beating State Under Simulated Left Ventricular Restoration
Heart failure was induced by cardiac pacing to evaluate myocardial flow distribution of the open ventricle during delivery of either cardioplegia or in the beating state during simulated left ventricular restoration.
Differences in Platelet Growth Factor Release and Leucocyte Kinetics During Autologous Platelet Gel Formation
Three commercial systems for whole blood separation were compared to obtain the buffy coat composed of platelet-rich plasma (BC-PRP) and leucocytes .
The Impact of Tissue Factor Pathway Inhibitor on Coagulation Kinetics Determined by Thrombelastography
Thrombelastography (TEG) is often used to monitor hemostasis in the perioperative period, and TFPI could potentially affect the diagnostic interpretation of TEG-based data, given its inhibition of both common and TF coagulation pathways. Thus, in this study we characterized the effect of TFPI on coagulation kinetics via TEG.
An Experience With Cardiopulmonary Bypass in HIV-Infected Patients
Having noted the good clinical status of some HIV patients who were referred for but refused surgery, we undertook surgery with the aim of determining outcome, risk-to-benefit ratio and, if possible, the effect of surgery with cardiopulmonary bypass (CPB) on the progression of their HIV disease.
Aprotinin Improves Cerebral Protection: Evidence From a Survival Porcine Model
The goal of the study was to test the hypothesis that aprotinin could reduce cerebral injury after low-flow cardiopulmonary bypass and deep hypothermic circulatory arrest.
FDA Advisory Committee Strongly Endorses Use of Trasylol® in CABG Surgery Patients
Bayer was glad to participate in today’s advisory committee meeting held by the Cardiovascular and Renal Drugs Division of the U.S. Food and Drug Administration (FDA). This session provided an open forum in which to discuss the complex scientific issues surrounding the risk/benefit profile of Trasylol® (aprotinin injection) in detail.
Platelet Gel Sealant Use in Rhytidectomy
Quantitative assessments of postoperative drain fluid outputs were compared in subjects who did and did not receive platelet gel treatment.