Is There Really a Clinical Benefit of Using Minimized Extracorporeal Circulation for Coronary Artery Bypass Grafting?
This prospective study was performed to evaluate whether minimized extracorporeal circulation has a clinical benefit for coronary artery surgery patients compared to standard extracorporeal circulation.
Is There Really a Clinical Benefit of Using Minimized Extracorporeal Circulation for Coronary Artery Bypass Grafting?
This prospective study was performed to evaluate whether minimized extracorporeal circulation has a clinical benefit for coronary artery surgery patients compared to standard extracorporeal circulation.
Perfusion Approaches to Blood Conservation
There are several perfusion techniques that can contribute to blood conservation. Minimizing existing circuit components, using mini-circuits and the maneuver of retrograde autologous priming can be considered steps in prime reduction.
Routine Use of the Direct thrombin Inhibitor Bivalirudin for Off-Pump Coronary Artery Bypass Grafting is Safe and Effective
The risk of heparin-induced adverse reactions dictates the need for a safe and effective alternative, particularly in off-pump coronary artery bypass (OPCAB) surgery, an approach associated with a perioperative prothrombotic condition that may negatively influence graft patency.
A Comparison of Activated Coagulation Time-Based Techniques for Anticoagulation During cardiac Surgery With Cardiopulmonary Bypass
This study compared the efficacy of a modified ACT-based system versus an HMS (Hepcon; Medtronic Inc, Minneapolis, MN) for CPB anticoagulation.
FDA Never Inspected Chinese Plant Making Baxter’s Heparin
A Chinese manufacturing plant that was never inspected by the U.S. Food and Drug Administration could be the source of a potentially deadly allergic reaction experienced by hundreds of U.S. patients infused with Baxter International Inc.'s blood thinner heparin.
Single-Stage Sinus Augmentation With Cancellous Iliac Bone and Anorganic Bovine Bone in the Presence of Platelet-Rich Plasma in the Miniature Pig
Aim: The aim of the present study was to evaluate the osseointegration of dental implants and bone formation in maxillary sinus grafting with autologous and anorganic bovine bone in the presence of platelet-rich plasma (PRP) in an established animal model. Material and methods: We performed bilateral maxillary sinus augmentation with 50% anorganic bovine bone and simultaneously inserted a titanium screw implant in five minature pigs. Six hundred microlitre autologous PRP were added to the left side (test). The right side (no PRP) served as control. Polychrome sequential labeling was performed. The animals were sacrificed 6 weeks after surgery. Undecalcified ground sections were evaluated by microradiography, digitized histomorphometry and under fluorescent light. Results: The mean bone implant content in the test and control group was 8.4% and 17.3% respectively (P=0.042). The mean height of newly formed mineralized bone in the augmented area of the test group was 3.6 mm and 5.7 mm respectively (P=0.342). In the PRP group, the mean area of newly formed bone in the base of the sinus was enhanced (75.23%) as compared to the control side (51.8%) (P=0.020(*)). Although PRP enhanced bone formation at the base of the maxillary sinus, it neither improved osseointegration of dental implants nor bone in-growth into the bone substitute under the selected experimental conditions.
Avoiding Leukocyte Contamination and Early Platelet Activation in Platelet-Rich Plasma
The objective of this study was to describe a new platelet-rich plasma (PRP) protocol with a reduced concentration of leukocytes and intact platelets.
Evaluation of a New Platelet Function Analyzer in Cardiac Surgery: A Comparison of Modified Thromboelastography and Whole-Blood Aggregometry
Therefore, a new whole-blood platelet function analyzer was compared with thromboelastography in predicting postoperative hemostatic outcomes as measured by blood loss and blood product use.
Platelet-Rich Fibrin: Evolution of a Second-Generation Platelet Concentrate
This article describes the evolution of this novel platelet concentrate, referred to as PRF.
Clinical Experience With Assisted Venous Drainage Cardiopulmonary Bypass in Elective Cardiac Reoperations
Our experience with centrifugal pump-assisted venous drainage in cardiac reoperations has shown excellent results, with reduced risk of damage to vital structures on sternal reentry.
Effect of Perfusion Temperature on the Inflammatory Response During Pediatric Cardiac Surgery
The aim of this prospective study was to compare the inflammatory response in children undergoing CPB for repair of congenital heart defects, randomized to mild or moderate hypothermia.