A Platelet Rich Plasma (PRP) Based Membrane as a Periosteal Substitute with Enhanced Osteogenic and Angiogenic Properties: a New Concept for Bone Repair
We propose a periosteal substitute engineered using a platelet rich plasma (PRP) membrane incorporating autologous bone marrow derived mesenchymal stem cells (PRP/BMSC gel membrane) to be wrapped around an osteoconductive scaffold for regeneration of compromised bone defects.
The Effect of Cardiopulmonary Bypass Prime Volume on the Need for Blood Transfusion After Pediatric Cardiac Surgery
There is increasing awareness that erythrocyte transfusions after pediatric cardiac surgery have deleterious effects. Despite reports of decreased transfusion requirements associated with smaller cardiopulmonary bypass circuits, the relationship between circuit prime volume and need for transfusion has not been systematically examined.
A Systematic Evaluation of the Core Communication Skills Expected of a Perfusionist
The objective of this systematic evaluation was to identify the sentinel standards necessary to obtain a core level of communication required of a clinical perfusionist during cardiopulmonary bypass (CPB).
Hemoglobin Trends in Isolated Coronary Artery Bypass Grafting Performed Off-Pump and With Standard and Mini Circuits
This study was undertaken to compare the perioperative hemoglobin curves of isolated coronary artery bypass grafting performed with minimized extracorporeal circulation, traditional cardiopulmonary bypass, and off-pump technique.
Comparison of the Effects of Three Cell Saver Devices on Erythrocyte Function During Cardiopulmonary Bypass Procedure-A Pilot Study
The purpose of this study was to evaluate three commercially available cell saver (CS) devices in terms of erythrocyte function and the quality of washed RBCs during cardiopulmonary bypass (CPB).
Residual Blood Processing by Centrifugation, Cell Salvage or Ultrafiltration in Cardiac Surgery: Effects on Clinical Hemostatic and Ex-vivo Rheological Parameters
The study compared the effects of three blood concentration techniques after cardiopulmonary bypass on clinical hemostatic and ex-vivo rheological parameters.
Conventional Aortic Valve Replacement in Transcatheter Aortic Valve Implantation Candidates: A 5-Year Experience
Patient selection for transcatheter aortic valve implantation (TAVI) remains highly controversial. Some screened patients subsequently undergo conventional aortic valve replacement (AVR) because they are unsuitable TAVI candidates. This study examined the indications and outcomes for these patients, thereby determining the efficacy of the screening process.
Autologous Platelet-rich Plasma: Effect on Sternal Healing in the Sheep Model
We looked at the effects of plasma rich in growth factors (PRGF) as an agent on sternal bone healing.
The Effect of Platelet-rich Plasma on Wounds of OLETF Rats Using Expression of Matrix Metalloproteinase-2 and -9 mRNA
Complicated diabetic patients show impaired, delayed wound healing caused by multiple factors. A study on wound healing showed that platelet-rich plasma (PRP) was effective in normal tissue regeneration. Nonetheless, there is no evidence that when plateletrich plasma is applied to diabetic wounds, it normalizes the diabetic wound healing process. In this study, we have analyzed matrix metalloproteinase (MMP)-2, MMP-9 expression to investigate the effect of PRP on diabetic wounds.
Does Rotational Thromboelastometry (ROTEM) Improve Prediction of Bleeding After Cardiac Surgery?
Coagulopathy and massive bleeding are severe complications of cardiac surgery, particularly in procedures requiring prolonged cardiopulmonary bypass (CPB).
Evaluation of Four Pediatric Cardiopulmonary Bypass Circuits in Terms of Perfusion Quality and Capturing Gaseous Microemboli
This study compared four pediatric cardiopulmonary bypass (CPB) circuits with four different hollow-fiber membrane oxygenators and their specific reservoirs, Capiox RX15, Quadrox-i pediatric, Quadrox-i pediatric with integrated arterial filter (IAF) and KIDS D101, in a simulated CPB circuit identical to that used in the clinical setting at our institution to test their ability to maintain hemodynamic properties, remove gaseous microemboli (GME), and to test the amount of blood stolen by the arterial filter purge line.
Subtle Differences in Commercial Heparins Can Have Serious Consequences for Cardiopulmonary Bypass Patients: A Randomized Controlled Trial
Because in vitro testing failed to detect differences in the potency or protamine reversibility of the 2 heparin preparations, we conducted a parallel group, single-center, double-blind, randomized, controlled trial to compare the anticoagulant effects of Hepalean to those of PPC heparin in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass.