Bivalirudin for Alternative Anticoagulation in Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation (ECMO) offers therapeutic options in refractory respiratory and/or cardiac failure. Systemic anticoagulation with heparin is routinely administered. However, in patients with heparin-induced thrombocytopenia or heparin resistance, the direct thrombin inhibitor bivalirudin is a valid option and has been increasingly used for ECMO anticoagulation. We aimed at evaluating its safety and its optimal dosing for ECMO.
Protamine Reduces Bleeding Complications without Increasing the Risk of Stroke after Carotid Endarterectomy: A Meta-analysis
The aim was to evaluate the safety and efficacy of heparin reversal with protamine after completion of carotid endarterectomy (CEA), summarising the available data from both randomised and non-randomised studies.
Role of Intra-Aortic Balloon Pump in Off-Pump Coronary Artery Bypass
Hemodynamic deterioration during positioning of the heart has been the most critical complication of off-pump coronary artery bypass surgery. Pre-operative use of intra-aortic balloon pump has been shown to prevent this complication in high risk patients. The role of balloon pump in high risk patients has been questioned by our group. We modified the role of balloon pump in our patients, thus avoiding the conversion to cardiopulmonary bypass.
Adding Emulsified Isoflurane to Cardioplegia Solution Produces Cardiac Protection in a Dog Cardiopulmonary Bypass Model
This study investigated whether caridoplegia solution with Emulsified Isoflurane (EI) could improve cardiaoprotection in a dog CPB model of great similarity to clinical settings.
Efficacy of sutureless aortic valves in minimally invasive cardiac surgery: an evolution of the srugical techniques.
Sutureless aortic valve prostheses have the potential of shortening surgical time, but if this results in improved clinical outcome remains to be determined. The aim of this study was to compare the outcome of patients undergoing conventional vs minimally invasive AVR, with either a stented or sutureless bioprosthesis.
Sevoflurane and Isoflurane – Pharmacokinetics, Hemodynamic Stability and Cardioprotective Effects during Cardiopulmonary Bypass
This study aimed to evaluate the pharmacokinetic profiles of sevoflurane and isoflurane during the use of a minimized extracorporal circulation to perform coronary artery bypass graft surgery.
A SupraInstitutional Network for Remote Extracorporeal Life Support : A Retrospective Cohort Study
The study sought to evaluate patient outcome within the Düsseldorf Extracorporeal Life Support (ECLS) Network, a suprainstitutional network for rapid-response remote ECLS and to define survival-based predictors.
Refractory Cardiogenic Shock Treated By Veno-Arterial Ecmo; Prognostic Role Of Lactate
Refractory cardiogenic shock is characterized by severe hemodynamic instability with high mortality rate. In most critical patients extracorporeal membrane oxygenation (ECMO) is the only therapy available nowadays that gives a possibility to survive.On these bases we investigated the use of percutaneous veno-arterial ECMO as treatment for cardiogenic shock in our Cardiac Intensive Care Unit and tried to define prognostic factors.
TEG®- or ROTEM®-Based Individualized Goal-Directed Coagulation Algorithms: Don’t Wait–Act Now
TEG® and ROTEM® allow prediction of massive transfusion requirement and mortality, and creation of goal-directed, individualized coagulation algorithms that may improve patient outcome.
Factors Associated with Prolonged Length of Stay Following Cardiac Surgery in a Major Referral Hospital in Oman: A Retrospective Observational Study
This study identified factors influencing prolonged postoperative length of stay (LOS) following cardiac surgery and devised a predictive model for prolonged LOS in the cardiac intensive care unit (CICU).
Pulmonary Artery Rupture as a Complication of Swan-Ganz Catheter Application. Diagnosis and Endovascular Treatment: A Single Centre’s Experience
This paper presents two distinct forms of iatrogenic pulmonary artery rupture (PAR) treated endovascularly using different vascular devices.
Point-of-Care Thromboelastography/Thromboelastometry-Based Coagulation Management in Cardiac Surgery: A Meta-Analysis of 8332 Patients
In this meta-analysis, we aimed to determine the current evidence for or against point-of-care tests (POCT)-guided algorithm in patients with severe bleeding after cardiac surgery.