Fibrinogen Concentrate Reduces Intraoperative Bleeding when used as First-Line Hemostatic Therapy During Major Aortic Replacement Surgery: Results from a Randomized, Placebo-Controlled Trial
We assessed whether fibrinogen concentrate as targeted first-line hemostatic therapy was more effective than placebo or a standardized transfusion algorithm in controlling coagulopathic bleeding in patients undergoing major aortic surgery.
Mini-Extracorporeal Circulation Minimizes Coagulation Abnormalities and Ameliorates Pulmonary Outcome in Coronary Artery Bypass Grafting Surgery
Our study suggests that MECC induces less coagulation disorders, leading to lower postoperative blood loss and better postoperative lung function. This approach may be advantageous in high-risk patients.
Blood Product Conservation is Associated with Improved Outcomes and Reduced Costs after Cardiac Surgery
The purpose of this investigation was to determine whether a multi-institutional effort to reduce blood product use affects postoperative events aftercardiac surgical operations and to determine the influence of perioperative transfusion on risk-adjusted outcomes.
Transfusion of Leukocyte-Depleted RBCs Is Independently Associated With Increased Morbidity After Pediatric Cardiac Surgery
Transfusion of leukocyte-depleted RBCs within the first 48 hrs of PICU stay after cardiac surgery is independently associated with prolonged duration of mechanical ventilation.
The Predictive Value of Multiple Electrode Platelet Aggregometry (Multiplate) in Adult Cardiac Surgery
The purpose of this retrospective observational study is to analyze the value of multiple electrode platelet aggregometry (Multiplate analyzer, Verum Diagnostica, Munich) as a point-of-care (POC) device in adult cardiac surgical patients.
Perfusion Tubing: Standardized or Modify?
I applaud our adult colleagues in trying to do what is best for the patient even if standardized tubing packs have to be modified resulting in higher prices as some would argue.
Performance Analysis of EuroSCORE II Compared to the Original Logistic EuroSCORE and STS Scores for Predicting 30-Day Mortality After Transcatheter Aortic Valve Replacement
EuroSCORE II and the STS score are better calibrated than the logistic EuroSCORE but have moderate discrimination for predicting 30-day mortality after TAVR.
Cost Effectiveness of Transcatheter Aortic Valve Replacement Compared to Medical Management in Inoperable Patients with Severe Aortic Stenosis: Canadian Analysis Based on the PARTNER Trial Cohort B Findings
The objective was to estimate cost-effectiveness of TAVR via transfemoral access vs MM in surgically inoperable patients with severe AS from the Canadian public healthcare system perspective.
A Review of Antithrombotic Therapy for Transcatheter Aortic Valve Replacement
This review evaluates the current guidelines, trials, and registry data discussing antithrombotic regimens for TAVR.
Paravalvular Leak After Transcatheter Aortic Valve Replacement: The New Achilles’ Heel? A Comprehensive Review of the Literature
This literature review is an effort to consolidate current knowledge in this area to better understand the prevalence, progression, and impact of post-TAVR PVL and to help direct future efforts regarding the assessment, prevention, and treatment of this troublesome complication.
Vascular Access Complications: Diagnosis and Management
The incidence of vascular access site related complications ranges between 0.8 % to 1.8 % of diagnostic cardiac catheterization and up to 9 % of percutaneous coronary interventions.
Prevalence and Effect of Myocardial Injury After Transcatheter Aortic Valve Replacement
We aimed to assess the incidence and extent of myocardial injury after TAVR performed using transfemoral and transapical approaches.